ArticleThe Plant cell2016
A Metabolic Gene Cluster in the Wheat W1 and the Barley Cer-cqu Loci Determines β-Diketone Biosynthesis and Glaucousness.
Article in The Plant cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
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Who cites it
80 citing papers in PubMed, 152 citations in OpenAlex.
- Barley HvBODYGUARD1 controls cuticular specialisations regulated by SHINE transcription factors.The New phytologist · 2026Article
- Transcriptional control of cuticle formation during development.Journal of experimental botany · 2026Review
- Association mapping of wheat distinctness, uniformity, and stability traits identifies evidence ofFrontiers in plant science · 2026Article
- Genetic resource optimization: a core collection of tetraploid wheat from 2,254 NBRP-wheat accessions.BMC plant biology · 2025Article
- Integrated lipidomics and physiological analyses reveal the critical role of leaf sheath wax remodeling in wheat (Triticum aestivum L.) drought resistance.BMC plant biology · 2025Article
- Trait mapping differentiates loci influencing spike and flag leaf glaucousness in wheat.The plant genome · 2025Article
- Metabolic and genetic analysis links TRITERPENE SYNTHASE 12 to oleanolic acid biosynthesis in grape berry wax.Journal of experimental botany · 2025Article
- Comprehensive analysis of genomic loci associated with glaucousness in wheat (Physiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Article
- Challenges of translating Arabidopsis insights into crops.The Plant cell · 2025Review
- The dominant white color trait of the melon fruit rind is associated with epicuticular wax accumulation.Planta · 2024Article
- Biotechnological frontiers in harnessing allelopathy for sustainable crop production.Functional & integrative genomics · 2024Review
- Variation in a Poaceae-conserved fatty acid metabolic gene cluster controls rice yield by regulating male fertility.Nature communications · 2024Article
- A GDSL-motif Esterase/Lipase Affects Wax and Cutin Deposition and Controls Hull-Caryopsis Attachment in Barley.Plant & cell physiology · 2024Article
- Thermodynamic Analysis of n-Nonadecane (CMolecules (Basel, Switzerland) · 2024Article
- Gas Chromatography-Mass Spectrometry Metabolite Analysis Combined with Transcriptomics Reveals Genes Involved in Wax Biosynthesis inInternational journal of molecular sciences · 2024Article
- A century of studying plant secondary metabolism-From "what?" to "where, how, and why?"Plant physiology · 2024Review
- A long non-coding RNA functions as a competitive endogenous RNA to modulate TaNAC018 by acting as a decoy for tae-miR6206.Plant molecular biology · 2024Article
- Cuticular wax biosynthesis in blueberries (Horticulture research · 2024Article
- Cuticular wax in wheat: biosynthesis, genetics, and the stress response.Frontiers in plant science · 2024Review
20 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
19 authors at 8 institutions in 4 countries.
Funding
Abstract
The glaucous appearance of wheat (Triticum aestivum) and barley (Hordeum vulgare) plants, that is the light bluish-gray look of flag leaf, stem, and spike surfaces, results from deposition of cuticular β-diketone wax on their surfaces; this phenotype is associated with high yield, especially under drought conditions. Despite extensive genetic and biochemical characterization, the molecular genetic basis underlying the biosynthesis of β-diketones remains unclear. Here, we discovered that the wheat W1 locus contains a metabolic gene cluster mediating β-diketone biosynthesis. The cluster comprises genes encoding proteins of several families including type-III polyketide synthases, hydrolases, and cytochrome P450s related to known fatty acid hydroxylases. The cluster region was identified in both genetic and physical maps of glaucous and glossy tetraploid wheat, demonstrating entirely different haplotypes in these accessions. Complementary evidence obtained through gene silencing in planta and heterologous expression in bacteria supports a model for a β-diketone biosynthesis pathway involving members of these three protein families. Mutations in homologous genes were identified in the barley eceriferum mutants defective in β-diketone biosynthesis, demonstrating a gene cluster also in the β-diketone biosynthesis Cer-cqu locus in barley. Hence, our findings open new opportunities to breed major cereal crops for surface features that impact yield and stress response.
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