ArticleInternational journal of legal medicine2017
Evaluation of the genetic parameters and mutation analysis of 22 STR loci in the central Chinese Han population.
Article in International journal of legal medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 20 citations in OpenAlex.
- Reinvestigation of a paternity case with three CODIS core STR inconsistencies using MPS-based multi‑marker analysis.Scientific reports · 2026Article
- Forensic characteristics and genetic variations of Han Chinese population in Shenzhen revealed by 23 autosomal STRs.Frontiers in genetics · 2026Article
- A forensic population database of autosomal STR and X-STR markers in the Qiang ethnic minority of China.Heliyon · 2023Article
- Article
- Forensic characteristics and phylogenetic analyses of one branch of Tai-Kadai language-speaking Hainan Hlai (Ha Hlai) via 23 autosomal STRs included in the HuaxiaMolecular genetics & genomic medicine · 2020Article
- The Ong Be language-speaking population in Hainan Island: genetic diversity, phylogenetic characteristics and reflections on ethnicity.Molecular biology reports · 2019Article
- Genetic structure and polymorphism analysis of Xinjiang Hui ethnic minority based on 21 STRs.Molecular biology reports · 2018Article
- Phylogenic analysis and forensic genetic characterization of Chinese Uyghur group via autosomal multi STR markers.Oncotarget · 2017Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
At present, the Han nationality is China's main ethnic group and also the most populous nation in the world. This is a great resource to study microsatellite mutations and for the study of ethnogeny. The aim of this study is to investigate the genetic polymorphisms and mutations of 22 autosomal STR loci in 2475 individuals from Henan province, China. DNA is amplified and genotyped using PowerPlex™24 system. The gene frequencies, forensic parameters, and the mutation rate of the 22 STR loci are analyzed. A total of 295 alleles are observed in this Henan Han population, and the allelic frequencies ranged from 0.0003 to 0.5036. In order to investigate the genetic relationships between the Henan Han and the other 14 different populations, our present data were compared with previously published data for the same 15 STR loci. The results indicated that the Henan Han had closer genetic relationships the groups including Minnan Han, Maonan, Yi and Guangdong Han groups while the South morocco population, the Moroccan population, the Malay group, and the Uigur stand away from Henan Han. Except of D2S441, D13S317, PentaE, D2S1338, D5S818, TPOX and D19S433, the mutation events are found in the other 15 STR loci. A total of 40 mutation events are observed in the 15 STR loci. The mutation rates are ranged from 0 to 4.85 × 10
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