ReviewNature reviews. Neuroscience2016
Integrated information theory: from consciousness to its physical substrate.
Review in Nature reviews. Neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 555 papers.
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Who cites it
555 citing papers in PubMed.
- The entropic brain today.Brain : a journal of neurology · 2026Review
- Mechanisms of transcranial magnetic brain stimulation.Physiological reviews · 2026Review
- Thalamic modulation of cortical linearity across arousal states.Science advances · 2026Article
- The Emergence of Consciousness.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Deep Brain Stimulation for Disorders of Consciousness: From Mesocircuit Mechanisms to Circuit-Guided Precision Neuromodulation.Neuroscience bulletin · 2026Review
- Dynamic Global and Local Enhancement of Theta-Band Functional Networks as Neural Markers of Spinal Cord Stimulation Efficacy in Disorders of Consciousness.CNS neuroscience & therapeutics · 2026Article
- Principal bundle geometry of qualia: Understanding the quality of consciousness from symmetry.PNAS nexus · 2026Article
- Article
- A Sequential Markov Probabilistic Aggregation Algorithm for Causal Emergence in Markov Aggregation.Entropy (Basel, Switzerland) · 2026Article
- Thalamic oscillations distinguish natural states of consciousness in humans.Nature human behaviour · 2026Article
- Steps forward to synthetic consciousness measurement.Cognitive processing · 2026Article
- Thermodynamics of consciousness: Non-equilibrium brain dynamics track conscious states.Cell reports · 2026Article
- Consciousness in the Brain: An Integrative Review of Contemporary Theories.Brain sciences · 2026Review
- Advances in local field potential research in prolonged disorders of consciousness: a narrative review.Chinese neurosurgical journal · 2026Review
- A three-component dynamical index of consciousness-related neural organisation.Biological cybernetics · 2026Article
- Neuronal Microtubules and Radiofrequency Waves: The Quantum Core of Human Consciousness, Memory, and Pathway to Memory Enhancement/Recovery.International journal of molecular sciences · 2026Review
- Neural mechanisms of awareness of action.PNAS nexus · 2026Article
- Cortical neuron classes and recursive curvature collapse: a neurobiological model of conscious dynamics.Theory in biosciences = Theorie in den Biowissenschaften · 2026Article
- System-specific reductions of resting-state BOLD signal entropy in disorders of consciousness.Neuroradiology · 2026Article
- Article
495 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this Opinion article, we discuss how integrated information theory accounts for several aspects of the relationship between consciousness and the brain. Integrated information theory starts from the essential properties of phenomenal experience, from which it derives the requirements for the physical substrate of consciousness. It argues that the physical substrate of consciousness must be a maximum of intrinsic cause-effect power and provides a means to determine, in principle, the quality and quantity of experience. The theory leads to some counterintuitive predictions and can be used to develop new tools for assessing consciousness in non-communicative patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.