Evidence map›Paper›PMID 27224989›Full record

ArticleJournal of abnormal child psychology2017

Anxiety and Depression Symptom Dimensions Demonstrate Unique Relationships with the Startle Reflex in Anticipation of Unpredictable Threat in 8 to 14 Year-Old Girls.

Brady D Nelson, Greg Hajcak

Open access · greenAbstract read
In one paragraph

Article in Journal of abnormal child psychology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Beyond classical metrics: Generalizability theory across psychophysiological modalities.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2026
    Review
  3. Article
  4. Article
  5. Article
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  7. Article
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  10. Event-related potentials to acoustic startle probes during unpredictable threat are associated with individual differences in intolerance of uncertainty.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Pediatric OCD in the era of RDoC.Journal of obsessive-compulsive and related disorders · 2019
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Brady D NelsonDepartment of Psychology, Stony Brook University, Psychology B Building, Stony Brook, NY, 11794-2500, USA. brady.nelson@stonybrook.edu.
Greg HajcakDepartment of Psychology, Stony Brook University, Psychology B Building, Stony Brook, NY, 11794-2500, USA.
Stony Brook University · US

Funding

Trajectories of Reward Sensitivity and Depression Across AdolescenceR01MH097767 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI NELSON, BRADY D · 2012 to 2022
$6.0M
Anxiety Risk and Adolescence: Sensitivity to Unpredictable Threat and UncertaintyK01MH107808 · NIMH · STATE UNIVERSITY NEW YORK STONY BROOK · PI NELSON, BRADY D · 2015 to 2017
$531k
NIMH NIH HHS K01 MH107808NIMH NIH HHS R01 MH097767
6 · The paper itself

Abstract

There is growing evidence that heightened sensitivity to unpredictability is a core mechanism of anxiety disorders. In adults, multiple anxiety disorders have been associated with a heightened startle reflex in anticipation of unpredictable threat. Child and adolescent anxiety has been linked to an increased startle reflex across baseline, safety, and threat conditions. However, it is unclear whether anxiety in youth is related to the startle reflex as a function of threat predictability. In a sample of 90 8 to 14 year-old girls, the present study examined the association between anxiety symptom dimensions and startle potentiation during a no, predictable, and unpredictable threat task. Depression symptom dimensions were also examined given their high comorbidity with anxiety and mixed relationship with the startle reflex and sensitivity to unpredictability. To assess current symptoms, participants completed the self-report Screen for Child Anxiety Related Emotional Disorders and Children's Depression Inventory. Results indicated that social phobia symptoms were associated with heightened startle potentiation in anticipation of unpredictable threat and attenuated startle potentiation in anticipation of predictable threat. Negative mood and negative self-esteem symptoms were associated with attenuated and heightened startle potentiation in anticipation of unpredictable threat, respectively. All results remained significant after controlling for the other symptom dimensions. The present study provides initial evidence that anxiety and depression symptom dimensions demonstrate unique associations with the startle reflex in anticipation of unpredictable threat in children and adolescents.

Indexed as

AdolescentAnticipation, PsychologicalAnxietyChildDepressionFemaleHumansReflex, StartleAdolescenceAnxietyChildhoodDepressionStartleUnpredictability

Identifiers

PMID27224989
PMCPMC5124418
OpenAlexW2398804860

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.