ArticleAJR. American journal of roentgenology2016
Dual-Energy CT for Quantification of Urinary Stone Composition in Mixed Stones: A Phantom Study.
Article in AJR. American journal of roentgenology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 29 citations in OpenAlex.
- Layered structure of sialoliths compared with tonsilloliths and antroliths.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2024Article
- Demonstrating the Efficacy of Dual Energy Computer Tomography with Gemstone Spectral Imaging Software to Determine Mixed and Single Composition ex vivo Urolithiasis.Research and reports in urology · 2024Article
- Identification of biological components for sialolith formation organized in circular multi-layers.Scientific reports · 2023Article
- Quantitative X-ray phase contrast computed tomography with grating interferometry : Biomedical applications of quantitative X-ray grating-based phase contrast computed tomography.European journal of nuclear medicine and molecular imaging · 2021Review
- Revolution spectral CT for urinary stone with a single/mixed composition in vivo: a large sample analysis.World journal of urology · 2021Article
- Pre-operative Percutaneous Nephrolithotripsy Characterisation of Kidney Stones with Second-Generation Dual-Source Dual-Energy Computed Tomography.The Malaysian journal of medical sciences : MJMS · 2020Article
- Image Quality and Dose Comparison of Single-Energy CT (SECT) and Dual-Energy CT (DECT).Radiology research and practice · 2020Review
- Dual-energy CT: theoretical principles and clinical applications.La Radiologia medica · 2019Review
- Renal Stone Characterization using High Resolution Imaging Mode on a Photon Counting Detector CT System.Proceedings of SPIE--the International Society for Optical Engineering · 2017Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe purpose of this study was to assess the feasibility of using dual-energy CT to accurately quantify uric acid and non-uric acid components in urinary stones of mixed composition. MATERIALS AND
methodsA total of 24 urinary stones were analyzed with micro CT to serve as the reference standard for uric acid and non-uric acid composition. These stones were placed in water phantoms to simulate body attenuation of slim to obese adults and scanned with a third-generation dual-source CT scanner by use of dual-energy modes adaptively selected on the basis of phantom size. CT number ratio, which is distinct for different materials, was calculated for each pixel of the stones. Each pixel was then classified as uric acid and non-uric acid by comparison of the CT number ratio with preset thresholds ranging from 1.10 to 1.70. Minimal, maximal, and root-mean-square errors were calculated by comparing composition with the reference standard, and the threshold with the minimal root-mean-square error was determined. A paired t test was performed to compare the stone composition determined with dual-energy CT with the reference standard obtained with micro CT.
resultsThe optimal CT number ratio threshold ranged from 1.27 to 1.55, dependent on phantom size. The root-mean-square error ranged from 9.60% to 12.87% across all phantom sizes. Minimal absolute error ranged from 0.04% to 1.24% and maximal absolute error from 22.05% to 35.46%. Dual-energy CT and the reference micro CT did not differ significantly on uric acid and non-uric acid composition (paired t test, p = 0.20-0.96).
conclusionAccurate quantification of uric acid and non-uric acid composition in mixed stones is possible with dual-energy CT.
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