ReviewCurrent opinion in neurology2016
Transcranial brain stimulation: closing the loop between brain and stimulation.
Review in Current opinion in neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.
- How Can Transcranial Magnetic Stimulation Be Used to Modulate Episodic Memory?: A Systematic Review and Meta-Analysis.Frontiers in psychology · 2019Pooled it
- Reliability of resting-state EEG modulation by continuous and intermittent theta burst stimulation of the primary motor cortex: a sham-controlled study.Scientific reports · 2023Trial
- Inter-individual differences in baseline dynamic functional connectivity are linked to cognitive aftereffects of tDCS.Scientific reports · 2022Trial
- Bayesian Temporal Prediction: A Robust Algorithm for Real-Time EEG Phase-Dependent Brain Stimulation.IEEE transactions on bio-medical engineering · 2026Article
- The neurobiological synergy of transcranial magnetic stimulation and mindfulness-based interventions in treatment-resistant depression: a narrative review.Frontiers in psychiatry · 2026Review
- Transcranial magnetic stimulation from healthy brain aging to Alzheimer's disease: a review on mechanisms, therapeutic potential, and future clinical directions.Frontiers in aging neuroscience · 2026Review
- Lightweight EEG Phase Prediction Based on Channel Attention and Spatio-Temporal Parallel Processing.Brain sciences · 2025Article
- Chronic alcohol-induced brain states limit propagation of direct cortical stimulation.Scientific reports · 2025Article
- Next generation bioelectronic medicine: making the case for non-invasive closed-loop autonomic neuromodulation.Bioelectronic medicine · 2025Review
- A new index of cortical plasticity induced by paired associative stimulation to describe cognitive status in aged healthy subjects.Frontiers in physiology · 2025Article
- A review of ethical considerations for the medical applications of brain-computer interfaces.Cognitive neurodynamics · 2024Review
- Different Effect Sizes of Motor Skill Training Combined with Repetitive Transcranial versus Trans-Spinal Magnetic Stimulation in Healthy Subjects.Brain sciences · 2024Article
- Brain state-dependent repetitive transcranial magnetic stimulation for motor stroke rehabilitation: a proof of concept randomized controlled trial.Frontiers in neurology · 2024Article
- Closing the loop between brain and electrical stimulation: towards precision neuromodulation treatments.Translational psychiatry · 2023Review
- Closed-loop optimal and automatic tuning of pulse amplitude and width in EMG-guided controllable transcranial magnetic stimulation.Biomedical engineering letters · 2023Article
- Alpha modulation via transcranial alternating current stimulation in adults with attention-deficit hyperactivity disorder.Frontiers in psychology · 2023Review
- State-dependent effects of neural stimulation on brain function and cognition.Nature reviews. Neuroscience · 2022Review
- P300 ModulationFrontiers in psychiatry · 2022Article
- Article
- The effect of transcranial direct current stimulation combined with functional task training on motor recovery in stroke patients.Medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewTo discuss recent strategies for boosting the efficacy of noninvasive transcranial brain stimulation to improve human brain function. RECENT
findingsRecent research exposed substantial intra- and inter-individual variability in response to plasticity-inducing transcranial brain stimulation. Trait-related and state-related determinants contribute to this variability, challenging the standard approach to apply stimulation in a rigid, one-size-fits-all fashion. Several strategies have been identified to reduce variability and maximize the plasticity-inducing effects of noninvasive transcranial brain stimulation. Priming interventions or paired associative stimulation can be used to 'standardize' the brain-state and hereby, homogenize the group response to stimulation. Neuroanatomical and neurochemical profiling based on magnetic resonance imaging and spectroscopy can capture trait-related and state-related variability. Fluctuations in brain-states can be traced online with functional brain imaging and inform the timing or other settings of transcranial brain stimulation. State-informed open-loop stimulation is aligned to the expression of a predefined brain state, according to prespecified rules. In contrast, adaptive closed-loop stimulation dynamically adjusts stimulation settings based on the occurrence of stimulation-induced state changes. SUMMARY: Approaches that take into account trait-related and state-related determinants of stimulation-induced plasticity bear considerable potential to establish noninvasive transcranial brain stimulation as interventional therapeutic tool.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.