ArticlePhysics in medicine and biology2016
Investigation of assumptions underlying current safety guidelines on EM-induced nerve stimulation.
Article in Physics in medicine and biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Electric field calculation and peripheral nerve stimulation prediction for head and body gradient coils.Magnetic resonance in medicine · 2021Pooled it
- Action potential threshold variability for different electrostimulation models and its potential impact on occupational exposure limit values.Bioelectromagnetics · 2025Article
- Experimental validation of a PNS-optimized whole-body gradient coil.Magnetic resonance in medicine · 2024Article
- A Huygens' surface approach to rapid characterization of peripheral nerve stimulation.Magnetic resonance in medicine · 2022Article
- Evaluation of Peripheral Electrostimulation Thresholds in Human Model for Uniform Magnetic Field Exposure.International journal of environmental research and public health · 2021Article
- Optimizing selective stimulation of peripheral nerves with arrays of coils or surface electrodes using a linear peripheral nerve stimulation metric.Journal of neural engineering · 2020Article
- Prediction of peripheral nerve stimulation thresholds of MRI gradient coils using coupled electromagnetic and neurodynamic simulations.Magnetic resonance in medicine · 2019Article
- Sensitivity analysis of neurodynamic and electromagnetic simulation parameters for robust prediction of peripheral nerve stimulation.Physics in medicine and biology · 2018Article
- Functionalized Anatomical Models for Computational Life Sciences.Frontiers in physiology · 2018Article
- Numerical modeling of percutaneous auricular vagus nerve stimulation: a realistic 3D model to evaluate sensitivity of neural activation to electrode position.Medical & biological engineering & computing · 2017Article
- Predicting Magnetostimulation Thresholds in the Peripheral Nervous System using Realistic Body Models.Scientific reports · 2017Article
- Functionalized anatomical models for EM-neuron Interaction modeling.Physics in medicine and biology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
An intricate network of a variety of nerves is embedded within the complex anatomy of the human body. Although nerves are shielded from unwanted excitation, they can still be stimulated by external electromagnetic sources that induce strongly non-uniform field distributions. Current exposure safety standards designed to limit unwanted nerve stimulation are based on a series of explicit and implicit assumptions and simplifications. This paper demonstrates the applicability of functionalized anatomical phantoms with integrated coupled electromagnetic and neuronal dynamics solvers for investigating the impact of magnetic resonance exposure on nerve excitation within the full complexity of the human anatomy. The impact of neuronal dynamics models, temperature and local hot-spots, nerve trajectory and potential smoothing, anatomical inhomogeneity, and pulse duration on nerve stimulation was evaluated. As a result, multiple assumptions underlying current safety standards are questioned. It is demonstrated that coupled EM-neuronal dynamics modeling involving realistic anatomies is valuable to establish conservative safety criteria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.