Evidence map›Paper›PMID 27223254›Full record

ArticleChemical communications (Cambridge, England)2016

Chloride anion transporters inhibit growth of methicillin-resistant Staphylococcus aureus (MRSA) in vitro.

Andrew I Share, Khushali Patel, Cristina Nativi, Eun J Cho, Oscar Francesconi, Nathalie Busschaert, Philip A Gale, Stefano Roelens, Jonathan L Sessler

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Lipophilic mono-guanidinesRSC advances · 2026
    Article
  2. Article
  3. Heterocyclic-Fused Squaramides: Anionophores With Antimicrobial Activity.Chembiochem : a European journal of chemical biology · 2026
    Article
  4. Review
  5. A Single-Molecule Liposome Assay for Membrane Permeabilization.Angewandte Chemie (International ed. in English) · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Recent Advances in Bioactive Artificial Ionophores.Chembiochem : a European journal of chemical biology · 2021
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrew I ShareDepartment of Chemistry, The University of Texas, Austin, TX 78712-1224, USA. sessler@cm.utexas.edu.
Khushali Patel
Cristina Nativi
Eun J Cho
Oscar Francesconi
Nathalie Busschaert
Philip A Gale
Stefano Roelens
Jonathan L Sessler

Funding

POLYPYRROLE BASED ANION RECEPTORSR01GM058907 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI SESSLER, JONATHAN L · 1999 to 2010
$2.7M
Receptor and Carriers for Coupled Ion TransportR01GM103790 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI SESSLER, JONATHAN L, WILLIAMS, ROBERT O. · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM058907NIGMS NIH HHS R01 GM103790
6 · The paper itself

Abstract

A series of aminopyrrolic receptors were tested as anion transporters using POPC liposome model membranes. Many were found to be effective Cl(-) transporters and to inhibit clinical strains of Staphylococcus aureus growth in vitro. The best transporters proved effective against the methicillin-resistant Staphylococcus aureus (MRSA) strains, Mu50 and HP1173. Tris-thiourea tren-based chloride transporters were also shown to inhibit the growth of S. aureus in vitro.

Indexed as

Anion Transport ProteinsAnti-Bacterial AgentsChloridesLiposomesMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsMolecular StructureAnion Transport ProteinsAnti-Bacterial AgentsChloridesLiposomes

Identifiers

PMID27223254
PMCPMC4911636

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.