Evidence map›Paper›PMID 27222931›Full record

ArticleTransplantation2016

Isoform-Selective HDAC Inhibitor Therapy for Transplantation: Are We Ready for HDAC6?

Wayne W Hancock

Abstract readComment
In one paragraph

Article in Transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. HDAC10 deletion promotes Foxp3Scientific reports · 2020
    Article
  4. Histone/protein deacetylase inhibitor therapy for enhancement of Foxp3+ T-regulatory cell function posttransplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Wayne W Hancock1 Division of Transplant Immunology, Department of Pathology and Laboratory Medicine, and Biesecker Center for Pediatric Liver Diseases, Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

Funding

Class IIa HDAC and MEF2 Targeting to Promote Foxp3+ Treg Cell FunctionsR01AI123241 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI HANCOCK, WAYNE WILLIAM · 2016 to 2020
$2.1M
HAT Inhibition to Impair Foxp3+ Treg Function and Boost Anti-Tumor ImmunityR01CA158941 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI HANCOCK, WAYNE WILLIAM · 2011 to 2015
$1.7M
Foxp3+ Treg Cells & Primary Graft Dysfunction in Clinical Lung Tx RecipientsR01HL114468 · NHLBI · CHILDREN'S HOSP OF PHILADELPHIA · PI HANCOCK, WAYNE WILLIAM · 2012 to 2015
$1.7M
NCI NIH HHS R01 CA158941NHLBI NIH HHS R01 HL114468NIAID NIH HHS R01 AI123241
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Histone Deacetylase InhibitorsHistone DeacetylasesHistone Deacetylase 6HumansHydroxamic AcidsProtein IsoformsHistone Deacetylase 6Histone Deacetylase InhibitorsHistone DeacetylasesHydroxamic AcidsProtein Isoforms

Identifiers

PMID27222931
PMCPMC4961515

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.