ArticleAvicenna journal of phytomedicine
Effect of Coriandrum sativum hydroalcoholic extract and its essential oil on acetic acid- induced acute colitis in rats.
Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 38 citations in OpenAlex.
- Pharmacological and molecular insights into linalool-richVeterinary world · 2025Article
- Exploration of the potential therapeutic effects and targets of Coriandrum sativum on non-erosive esophagitis based on bioinformatics and molecular dynamics simulation.Scientific reports · 2025Article
- Plant Essential Oils as Healthy Functional Ingredients of Nutraceuticals and Diet Supplements: A Review.Molecules (Basel, Switzerland) · 2023Review
- Essential Oil fromMolecules (Basel, Switzerland) · 2023Review
- Ameliorative Effect of Aqueous and Hydroalcoholic Extracts ofAdvanced biomedical research · 2023Article
- Disease alleviating effects following prophylactic lemon and coriander essential oil treatment in mice with acute campylobacteriosis.Frontiers in microbiology · 2023Article
- Efficacy of Jawarish Shahi a herbal formulation in irritable bowel syndrome: An open-labeled single-arm clinical trial.Journal of traditional and complementary medicine · 2022Article
- Lycopodium Mitigates Oxidative Stress and Inflammation in the Colonic Mucosa of Acetic Acid-Induced Colitis in Rats.Molecules (Basel, Switzerland) · 2022Article
- Ethnobotanical and phytochemical aspects of the edible herb Coriandrum sativum L.Journal of food science · 2022Review
- Coriander Oil Reverses Dexamethasone-Induced Insulin Resistance in Rats.Antioxidants (Basel, Switzerland) · 2022Article
- Apiaceae Essential Oils: Boosters of Terbinafine Activity against Dermatophytes and Potent Anti-Inflammatory Effectors.Plants (Basel, Switzerland) · 2021Article
- COVID-19, cytokines, inflammation, and spices: How are they related?Life sciences · 2021Review
- Evaluation of the composition and in vitro antimicrobial, antioxidant, and anti-inflammatory activities of Cilantro (Saudi journal of biological sciences · 2021Article
- Traditional Herbal Medicine in Mesoamerica: Toward Its Evidence Base for Improving Universal Health Coverage.Frontiers in pharmacology · 2020Review
- Protective Effect ofInternational journal of preventive medicine · 2020Article
- The effects of crocin, mesalazine and their combination in the acetic acid-induced colitis in rats.Veterinary research forum : an international quarterly journal · 2019Article
- Chronic diseases, inflammation, and spices: how are they linked?Journal of translational medicine · 2018Review
- Chemical composition analysis andBiochimie open · 2017Article
- Anti-inflammatory effect ofAvicenna journal of phytomedicineArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to determine the protective effects of Coriandrum sativum on acetic acid-inducedcolitis in rats. C. sativum (Coriander) has long been used in Iranian traditional medicine and its use as an anti-inflammatory agent is still common in some herbal formulations. MATERIALS AND
methodsColitis was induced by intra-rectal administration of 2ml acetic acid 4% in fasted male Wistar rats. Treatment was carried out using three increasing doses of extract (250, 500, 1000 mg/kg) and essential oil (0.25, 0.5, 1 ml/kg) of coriander started 2 h before colitis induction and continued for a five-day period. Colon biopsies were taken for weighting, macroscopic scoring of injured tissue, histopathological examination and measuring myeloperoxidase (MPO) activity.
resultsColon weight was decreased in the groups treated with extract (500 and 1000 mg/kg) and essential oil (0.5 ml/kg) compared to the control group. Regarding MPO levels, ulcer severity and area as well as the total colitis index, same results indicating meaningful alleviation of colitis was achieved after treatment with oral extract and essential oil.
conclusionSince the present experiment was made by oral fractions of coriander thus the resulting effects could be due to both the absorption of the active ingredients and/or the effect of non-absorbable materials on colitis after reaching the colon. In this regard, we propose more toxicological and clinical experiments to warranty its beneficial application in human inflammatory bowel diseases.
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Identifiers
27222834PMC4877963W1780460818What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.