Evidence map›Paper›PMID 27222809›Full record

ArticleGenomics data2016

Identification of CELF1 RNA targets by CLIP-seq in human HeLa cells.

Olivier Le Tonquèze, Bernhard Gschloessl, Vincent Legagneux, Luc Paillard, Yann Audic

Open access · goldAbstract read
In one paragraph

Article in Genomics data, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Olivier Le TonquèzeCentre National de la Recherche Scientifique (CNRS), Institut de Génétique et Développement, UMR6290, Rennes, France.
Bernhard GschloesslCentre National de la Recherche Scientifique (CNRS), Institut de Génétique et Développement, UMR6290, Rennes, France.
Vincent LegagneuxCentre National de la Recherche Scientifique (CNRS), Institut de Génétique et Développement, UMR6290, Rennes, France.
Luc PaillardCentre National de la Recherche Scientifique (CNRS), Institut de Génétique et Développement, UMR6290, Rennes, France.
Yann AudicCentre National de la Recherche Scientifique (CNRS), Institut de Génétique et Développement, UMR6290, Rennes, France.
Centre National de la Recherche Scientifique · FRInstitut de génétique et de développement de Rennes · FRUniversité de Rennes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The specific interactions between RNA-binding proteins and their target RNAs are an essential level to control gene expression. By combining ultra-violet cross-linking and immunoprecipitation (CLIP) and massive SoliD sequencing we identified the RNAs bound by the RNA-binding protein CELF1, in human HeLa cells. The CELF1 binding sites deduced from the sequence data allow characterizing specific features of CELF1-RNA association. We present therefore the first map of CELF1 binding sites in human cells.

Indexed as

Alternative splicingCLIP-seqCUGBP1Homo sapiensRNA binding proteins

Identifiers

PMID27222809
PMCPMC4872370
OpenAlexW2338030457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.