ReviewJournal of advanced research2016
Phytochemistry, biological activities and potential of annatto in natural colorant production for industrial applications - A review.
Review in Journal of advanced research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed.
- Article
- Amazonian Nanobioeconomy 5.0: A Critical Integrative Review and Conceptual Framework Toward a Just Planetary Transition.Molecules (Basel, Switzerland) · 2026Review
- Techno-economic and Sustainability Assessment of Integrated Annatto Seed Biorefinery for Natural Pigments, Starch, and Nutraceuticals.ACS environmental Au · 2026Article
- Integrated Electrochemical and Biomedical Properties of Cu-Doped ZnO NPs Synthesized via Green Methods.ACS omega · 2026Article
- Sustaining colors of tradition: ethnobotanical study on natural dye plants in Guangxi, China.Journal of ethnobiology and ethnomedicine · 2026Article
- Chitosan nanocarriers loaded with Egyptian Calligonum comosum L'Hér. Extract: an eco-friendly approach for investigating triple-action biological activities.BMC complementary medicine and therapies · 2025Article
- New Cyclopeptide and γ‑Butyrolactone Derivatives from an Endophytic Strain of Cophinforma mamane.ACS omega · 2025Article
- TopicalFoot & ankle orthopaedics · 2025Article
- Synthesis and Applications of Fluorescent Chemosensors: A Review.Journal of fluorescence · 2024Review
- Bixin Combined with Metformin Ameliorates Insulin Resistance and Antioxidant Defenses in Obese Mice.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Effect of the Structural Modification of Plant Proteins as Microencapsulating Agents of Bioactive Compounds from Annatto Seeds (Foods (Basel, Switzerland) · 2024Article
- Comparative bioactivity assessment of bixin pigment and associated phytochemicals extracted from annatto seeds using conventional and green solvents.Journal of food and drug analysis · 2024Article
- One Health as a potential platform to rescue the neglected fruit trees in Yucatan, Mexico.Science in One Health · 2024Review
- Editorial: The One Health approach in the context of public health.Frontiers in public health · 2024Article
- Review
- Study of Essential Oil Isolated from Achiote (Antibiotics (Basel, Switzerland) · 2023Article
- Elucidation of the interaction of apocarotenoids with calf thymus DNA by biophysical techniques andIranian journal of basic medical sciences · 2023Article
- Therapeutic potential of bixin on inflammation: a mini review.Frontiers in nutrition · 2023Review
- Bioactive cellulose acetate nanofiber loaded with annatto support skeletal muscle cell attachment and proliferation.Frontiers in bioengineering and biotechnology · 2023Article
- Influence of Citrates and EDTA on Oxidation and Decarboxylation of Betacyanins in Red Beet (Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bixa orellana commonly known as annatto is one of the oldest known natural dye yielding plants native to Central and South America. Various parts of annatto have been widely used in the traditional medical system for prevention and treatment of a wide number of health disorders. The plethora of traditional uses has encouraged researchers to identify and isolate phytochemicals from all parts of this plant. Carotenoids, apocarotenoids, terpenes, terpenoids, sterols, and aliphatic compounds are main compounds found in all parts of this plant and are reported to exhibit a wide range of pharmacological activities. In recent years annatto has received tremendous scientific interest mainly due to the isolation of yellow-orange natural dye from its seeds which exhibits high biodegradability, low toxicity, and compatibility with the environment. Considerable research work has already been done and is currently underway for its applications in food, textile, leather, cosmetic, solar cells, and other industries. The present review provides up-to-date systematic and organized information on the traditional usage, phytochemistry and pharmacology of annatto. It also highlights its non-food industrial applications in order to bring more interest on this dye plant, identifies the existing gaps and provides potential for future studies. Studies reported in this review have demonstrated that annatto holds a great potential for being exploited as source of drugs and a potential natural dye. However, further efforts are required to identify extract biomolecules and their action mechanisms in exhibiting certain biological activities in order to understand the full phytochemical profile and the complex pharmacological effects of this plant.
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