Evidence map›Paper›PMID 27222552›Full record

ReviewDiabetes care2016

Bariatric Surgery in Obese Patients With Type 1 Diabetes.

John P Kirwan, Ali Aminian, Sangeeta R Kashyap, Bartolome Burguera, Stacy A Brethauer, Philip R Schauer

Registry-linked trialOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Diabetes care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06394479 (Evaluation of the Long-term Outcome After Bariatric Surgery in Patients With Type 1 Diabetes Mellitus), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
9.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06394479 completednot on this mapstarted 2019, after this paper: background citation

Evaluation of the Long-term Outcome After Bariatric Surgery in Patients With Type 1 Diabetes Mellitus

TypeobservationalSponsorSana Klinikum OffenbachRan2019 to 2020Enrolled50ConditionsBariatric Surgery Status in T1DArmsOutcome after bariatric surgery in patient with T1D
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
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  17. Obesity in Patients with Type 1 Diabetes: Links, Risks and Management Challenges.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

John P KirwanEndocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH.
Ali AminianBariatric and Metabolic Institute, Cleveland Clinic, Cleveland, OH aminiaa@ccf.org.
Sangeeta R KashyapEndocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH.
Bartolome BurgueraEndocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, OH Bariatric and Metabolic Institute, Cleveland Clinic, Cleveland, OH.
Stacy A BrethauerBariatric and Metabolic Institute, Cleveland Clinic, Cleveland, OH.
Philip R SchauerBariatric and Metabolic Institute, Cleveland Clinic, Cleveland, OH.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere is a paucity of data on the impact of bariatric surgery in type 1 diabetes (T1D). The aim of this review was to quantify the overall effects of bariatric surgery in obese patients with T1D.

methodsWe searched PubMed, Scopus, ISI Web of Knowledge, and Google Scholar from their inception to December 2015 to identify all relevant studies of bariatric surgery in adult obese patients with T1D.

resultsThe review included 17 studies with 107 individuals, including 10 case series and 7 case reports. Overall, the dominant procedure was gastric bypass (n = 70; 65%). All studies reported a significant reduction in excess weight. A significant reduction in weight-adjusted daily insulin requirements was shown in all case series except one. Pooled mean ± SD of pre- and postoperative glycated hemoglobin (HbA1c) for the entire cohort with available data (n = 96) was 8.4 ± 1.3% and 7.9 ± 1.1%, respectively (P = 0.01). In addition to common postoperative complications, profound glycemic changes (diabetic ketoacidosis and hypoglycemia) and gastrointestinal dysmotility symptoms (prolonged ileus and acute gastric remnant dilation) have been reported. No surgical mortality was reported.

conclusionsBariatric surgery leads to significant weight loss in severely obese patients with T1D and results in a significant improvement in insulin requirements and glycemic status. The favorable metabolic effects of bariatric surgery may facilitate medical management of and cardiovascular risk reduction in T1D in the setting of severe obesity. Diabetic ketoacidosis and hypoglycemia are potentially serious complications. Short-term results of bariatric surgery in patients with T1D are encouraging, but larger and longer-term studies are needed.

Indexed as

Bariatric SurgeryAdultBlood GlucoseCardiovascular DiseasesDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2HumansObesityPostoperative ComplicationsRisk FactorsBlood Glucose

Identifiers

PMID27222552
PMCPMC8310563
OpenAlexW2400544139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.