Evidence map›Paper›PMID 27221226›Full record

ReviewNeurotoxicology and teratology

Cross-generational THC exposure alters the developmental sensitivity of ventral and dorsal striatal gene expression in male and female offspring.

Henrietta Szutorisz, Gabor Egervári, James Sperry, Jenna M Carter, Yasmin L Hurd

Open access · greenAbstract readReview
In one paragraph

Review in Neurotoxicology and teratology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Review
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  7. Article
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  10. Article
  11. Article
  12. Review
  13. Cannabis as a Gateway Drug for Opioid Use Disorder.The Journal of law, medicine & ethics : a journal of the American Society of Law, Medicine & Ethics · 2020
    Article
  14. [Epigenetic effects of cannabis/tetrahydrocannabinol].Bulletin de l'Academie nationale de medecine · 2020
    Review
  15. Review
  16. Article
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Henrietta SzutoriszFriedman Brain Institute, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gabor EgerváriFriedman Brain Institute, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Friedman Brain Institute, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
James SperryFriedman Brain Institute, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jenna M CarterFriedman Brain Institute, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Yasmin L HurdFriedman Brain Institute, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Friedman Brain Institute, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address: yasmin.hurd@mssm.edu.
Icahn School of Medicine at Mount Sinai · USAllen Institute for Brain Science · US

Funding

Neurodevelopmental Effects of Cannabis and its Epigenetic RegulationR01DA030359 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HURD, YASMIN L. · 2011 to 2020
$5.5M
Multigenerational Epigenetic Effects of Cannabis ExposureR01DA033660 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HURD, YASMIN L. · 2012 to 2016
$2.3M
NIDA NIH HHS R01 DA030359NIDA NIH HHS R01 DA033660
6 · The paper itself

Abstract

Cannabis (Cannabis sativa, Cannabis indica) is the illicit drug most frequently abused by young men and women. The growing use of the drug has raised attention not only on the impact of direct exposure on the developing brain and behavior later in life, but also on potential cross-generational consequences. Our previous work demonstrated that adolescent exposure to Δ

Indexed as

Maternal ExposurePaternal ExposureAnimalsCorpus StriatumDronabinolExploratory BehaviorFemaleGene ExpressionLocomotionMaleNeuronal PlasticityRats, Long-EvansRNA, MessengerDronabinolRNA, MessengerCross-generational transmissionDevelopmentGenderMarijuanaStriatumSynaptic plasticity

Identifiers

PMID27221226
PMCPMC5118190
OpenAlexW2400615654

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.