ReviewThe British journal of nutrition2016
Nutrition and the circadian system.
Review in The British journal of nutrition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- The Association Between Disordered Eating and Sleep in Non-Clinical Populations-A Systematic Review and Meta-Analysis.Journal of sleep research · 2026Pooled it
- Effects of caffeine intake on pupillary parameters in humans: a systematic review and meta-analysis.Behavioral and brain functions : BBF · 2024Pooled it
- Best Time of Day for Strength and Endurance Training to Improve Health and Performance? A Systematic Review with Meta-analysis.Sports medicine - open · 2023Pooled it
- The Impact of Dietary Factors on the Sleep of Athletically Trained Populations: A Systematic Review.Nutrients · 2022Pooled it
- A Systematic Review of the Effect of Dietary Supplements on Cognitive Performance in Healthy Young Adults and Military Personnel.Nutrients · 2020Pooled it
- Trial
- Chronotype and social jetlag influence human circadian clock gene expression.Scientific reports · 2018Trial
- Optimizing Athlete Travel for Performance: A Scientific Blueprint for Athletes, Coaches, and Sports Medicine Staff.Sports medicine (Auckland, N.Z.) · 2026Review
- Association between mealtime regularity and breakfast frequency with postpartum depression in first-time Japanese mothers: a cross-sectional study.BMC pregnancy and childbirth · 2026Article
- Chrononutrition, Body Composition, and Resting Metabolic Rate Among College Students: A Cross-Sectional Study.Nutrients · 2026Article
- Biochemical mechanism of the mammalian circadian clock.FEBS letters · 2026Review
- Links between psychological distress, late chronotype, and impaired sleep quality in survivors of sexual assault.Frontiers in psychology · 2026Article
- Circadian nutrition and obesity: timing as a nutritional strategy.Journal of health, population, and nutrition · 2025Review
- Cross-sectional associations between meal timing patterns and diet quality indices in Iranian women.Scientific reports · 2025Article
- Chrononutrition and Energy Balance: How Meal Timing and Circadian Rhythms Shape Weight Regulation and Metabolic Health.Nutrients · 2025Review
- The diverse roles of the circadian clock in cancer.Nature cancer · 2025Review
- Association of Overnight Fasting Duration and Meal Frequency with Glucose and Lipid Metabolism During Pregnancy: A Cross-Sectional Study.Nutrients · 2025Article
- Article
- Mechanistic study on electroacupuncture-regulated circadian autophagy for inhibiting ferroptosis in hippocampal neurons and alleviating depression-like behaviors in adulthood induced by early chronic sleep deprivation.Frontiers in neurology · 2025Article
- LncRNA-MSTRG.19083.1 Targets NTRK2 as a miR-429-y Sponge to Regulate Circadian Rhythm via the cAMP Pathway in Yak Testis and Cryptorchidism.International journal of molecular sciences · 2024Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The human circadian system anticipates and adapts to daily environmental changes to optimise behaviour according to time of day and temporally partitions incompatible physiological processes. At the helm of this system is a master clock in the suprachiasmatic nuclei (SCN) of the anterior hypothalamus. The SCN are primarily synchronised to the 24-h day by the light/dark cycle; however, feeding/fasting cycles are the primary time cues for clocks in peripheral tissues. Aligning feeding/fasting cycles with clock-regulated metabolic changes optimises metabolism, and studies of other animals suggest that feeding at inappropriate times disrupts circadian system organisation, and thereby contributes to adverse metabolic consequences and chronic disease development. 'High-fat diets' (HFD) produce particularly deleterious effects on circadian system organisation in rodents by blunting feeding/fasting cycles. Time-of-day-restricted feeding, where food availability is restricted to a period of several hours, offsets many adverse consequences of HFD in these animals; however, further evidence is required to assess whether the same is true in humans. Several nutritional compounds have robust effects on the circadian system. Caffeine, for example, can speed synchronisation to new time zones after jetlag. An appreciation of the circadian system has many implications for nutritional science and may ultimately help reduce the burden of chronic diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.