Evidence map›Paper›PMID 27221129›Full record

ArticleBMJ open2016

Moving forward through consensus: protocol for a modified Delphi approach to determine the top research priorities in the field of orthopaedic oncology.

Patricia Schneider, Nathan Evaniew, Juan Sebastian Rendon, Paula McKay, R Lor Randall, Robert Turcotte, Roberto Vélez, Mohit Bhandari, Michelle Ghert, PARITY Investigators

Abstract read
In one paragraph

Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Patricia SchneiderDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0003-1425-0687
Nathan EvaniewDepartment of Surgery, McMaster University, Hamilton, Ontario, Canada.
Juan Sebastian RendonDepartment of Surgery, McMaster University, Hamilton, Ontario, Canada.
Paula McKayDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada.
R Lor RandallDepartment of Orthopaedics, University of Utah, Salt Lake City, Utah, USA.
Robert TurcotteDivision of Orthopaedic Surgery, McGill University, Montreal, Quebec, Canada.
Roberto VélezTumour Unit, Department of Orthopaedic Surgery and Traumatology, Hospital Vall d'Hebron, Barcelona, Catalunya, Spain.
Mohit BhandariDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Michelle GhertDepartment of Surgery, McMaster University, Hamilton, Ontario, Canada Juravinski Cancer Centre, Hamilton Health Sciences, Hamilton, Ontario, Canada.
PARITY Investigators

Funding

CIHR MOP-1371
6 · The paper itself

Abstract

introductionOrthopaedic oncology researchers face several obstacles in the design and execution of randomised controlled trials, including finite fiscal resources to support the rising costs of clinical research and insufficient patient volume at individual sites. As a result, high-quality research to guide clinical practice has lagged behind other surgical subspecialties. A focused approach is imperative to design a research programme that is economical, streamlined and addresses clinically relevant endpoints. The primary objective of this study will be to use a consensus-based approach to identify research priorities for international clinical trials in orthopaedic oncology. METHODS AND ANALYSIS: We will conduct a 3-phase modified Delphi method consisting of 2 sequential rounds of anonymous web-based questionnaires (phases I and II), and an in-person consensus meeting (phase III). Participants will suggest research questions that they believe are of particular importance to the field (phase I), and individually rate each proposed question on 5 criteria (phase II). Research questions that meet predetermined consensus thresholds will be brought forward to the consensus meeting (phase III) for discussion by an expert panel. Following these discussions, the expert panel will be asked to assign scores for each research question, and research questions meeting predetermined criteria will be brought forward for final ranking. The expert panel will then be asked to rank the top 3 research questions, and these 3 research questions will be distributed to the initial group of participants for validation. ETHICS AND DISSEMINATION: An ethics application is currently under review with the Hamilton Integrated Research Ethics Board in Hamilton, Ontario, Canada. The results of this initiative will be disseminated through peer-reviewed publications and conference presentations.

Indexed as

Biomedical ResearchOrthopedicsResearch DesignSurgical OncologyBone NeoplasmsConsensusDelphi TechniqueHumansLower ExtremityMulticenter Studies as TopicRandomized Controlled Trials as TopicSarcomaConsensusDelphi studyResearch priorities

Identifiers

PMID27221129
PMCPMC4885431

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.