ArticleBMC public health2016
Parental smoking and cessation during pregnancy and the risk of childhood asthma.
Article in BMC public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 79 citations in OpenAlex.
- Parental smoke exposure before age 15 years and offspring asthma trajectories from ages 7 to 53 years.ERJ open research · 2026Article
- Exploring the Potential Roles ofInternational journal of molecular sciences · 2025Article
- The Effect of Environmental Factors, Health Behaviors, and Psychosocial Aspects on Allergic Diseases in Korean Adolescents.Medicina (Kaunas, Lithuania) · 2025Article
- Associations of Maternal Smoking During Pregnancy and Genetic Susceptibility with Incident Asthma from a Cohort Study.Prevention science : the official journal of the Society for Prevention Research · 2025Article
- Prevalence of Wheezing and Its Association with Environmental Tobacco Smoke Exposure among Rural and Urban Preschool Children in Mpumalanga Province, South Africa.International journal of environmental research and public health · 2024Article
- Sociodemographic factors, health behavior, parental or workplace smoking, and adult asthma risk in the United States.Work (Reading, Mass.) · 2024Article
- The Association between Vitamin D, Interleukin-4, and Interleukin-10 Levels and CD23+ Expression with Bronchial Asthma in Stunted Children.Biomedicines · 2023Article
- Developmental origins of health and disease: Impact of paternal nutrition and lifestyle.Pediatric investigation · 2023Review
- Maternal smoking status before and during pregnancy and bronchial asthma at 3 years of age: a prospective cohort study.Scientific reports · 2023Article
- How an Immune-Factor-Based Formulation of Micro-Immunotherapy Could Interfere with the Physiological Processes Involved in the Atopic March.International journal of molecular sciences · 2023Review
- Advances in respiratory physiology in mouse models of experimental asthma.Frontiers in physiology · 2023Review
- Pregnant women's beliefs about third-hand smoke and exposure to tobacco smoke.Central European journal of public health · 2022Article
- Association of Maternal Tobacco Use During Pregnancy With Preadolescent Brain Morphology Among Offspring.JAMA network open · 2022Article
- Mannose-binding lectin 2 gene polymorphisms and predisposition to allergic bronchial asthma in a western Romanian children population: an observational study.The Journal of international medical research · 2022Observational
- Time-Specific Factors Influencing the Development of Asthma in Children.Biomedicines · 2022Review
- Associations of early-life factors and indoor environmental exposure with asthma among children: a case-control study in Chongqing, China.World journal of pediatrics : WJP · 2022Article
- Maternal tobacco smoking and offspring autism spectrum disorder or traits in ECHO cohorts.Autism research : official journal of the International Society for Autism Research · 2022Article
- Prenatal and Perinatal Environmental Influences Shaping the Neonatal Immune System: A Focus on Asthma and Allergy Origins.International journal of environmental research and public health · 2021Review
- Trends of maternal waterpipe, cigarettes, and dual tobacco smoking in Jordan. A decade of lost opportunities.PloS one · 2021Article
- Factors Associated with the Development of Childhood Asthma in Japan: A Nationwide Longitudinal Study.Maternal and child health journal · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the association between maternal and paternal smoking during pregnancy, and asthma among offspring.
methodsWe conducted a hospital-based birth retrospective observational birth cohort study in a University-based Obstetrics and Gynecology Department, Kuopio University Hospital, Finland. 39 306 women, delivering between 1989 and 2006, were linked to the national register for asthma reimbursement for their offspring (2641 asthmatics). Pregnancy factors were recorded during pregnancy.
resultsThe risk of asthma was significantly elevated if both parents smoked (aOR 3.7; 95 % Cl 3.2-4.4) and it remained high in only paternal smoking families (aOR 2.9; 95 % Cl 2.5-3.3) as well as only maternal smoking families (aOR 1.7; 95 % Cl 1.2-2.2). Paternal cessation of smoking during pregnancy seemed to reduce the risk of asthma regardless of maternal smoking (aOR 0.3-0.4).
conclusionsParental smoking, and especially paternal smoking, was significantly associated with the risk of asthma in offspring and paternal cessation of smoking during pregnancy was associated with a decreased risk of childhood asthma regardless of maternal smoking. The results indicate that both parents should be encouraged to quit smoking during pregnancy, since it is a relatively easy and cheap way to reduce the risk of asthma in offspring.
trial registrationThe study is registered in Kuopio University Hospital register (TUTKI): ID5302448.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.