Evidence map›Paper›PMID 27220363›Full record

ArticleAutism research : official journal of the International Society for Autism Research2016

Autism-relevant behaviors are minimally impacted by conditional deletion of Pten in oxytocinergic neurons.

Amy E Clipperton-Allen, Youjun Chen, Damon T Page

Abstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. iScience · 2022
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. The Role of PTEN in Neurodevelopment.Molecular neuropsychiatry · 2020
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amy E Clipperton-AllenDepartment of Neuroscience, Scripps Research Institute, Jupiter, Florida.
Youjun ChenDepartment of Neuroscience, Scripps Research Institute, Jupiter, Florida.
Damon T PageDepartment of Neuroscience, Scripps Research Institute, Jupiter, Florida.
Scripps Research Institute · US

Funding

Impact of Pten mutations on brain growth and social behavioral development.R01MH105610 · NIMH · SCRIPPS FLORIDA · PI PAGE, DAMON THERON · 2015 to 2019
$2.4M
NIMH NIH HHS R01 MH105610
6 · The paper itself

Abstract

Germline heterozygous mutations in Pten (phosphatase and tensin homolog) are associated with macrocephaly and autism spectrum disorders (ASD). Pten germline heterozygous (Pten

Indexed as

NeuronsAnimalsAutistic DisorderBehavior, AnimalBrainDisease Models, AnimalFemaleMaleMiceMice, Inbred C57BLMice, KnockoutOxytocinPhenotypePTEN PhosphohydrolaseOxytocinPTEN PhosphohydrolasePten protein, mouseanxiety-like behaviorautism spectrum disorderhypertrophyoxytocinphosphatase and tensin homologsocial behavior

Identifiers

PMID27220363
PMCPMC6467524
OpenAlexW2403334536

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.