Evidence map›Paper›PMID 27219818›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2017

The Predictors study: Development and baseline characteristics of the Predictors 3 cohort.

Yaakov Stern, Yian Gu, Stephanie Cosentino, Martina Azar, Siobhan Lawless, Oksana Tatarina

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  4. Validation and demonstration of a new comprehensive model of Alzheimer's disease progression.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Article
  5. Article
  6. Article
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  10. Article
  11. Letter.Alzheimer's & dementia (Amsterdam, Netherlands) · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yaakov SternCognitive Neuroscience Division, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA. Electronic address: ys11@columbia.edu.
Yian GuCognitive Neuroscience Division, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Stephanie CosentinoCognitive Neuroscience Division, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Martina AzarCognitive Neuroscience Division, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Siobhan LawlessCognitive Neuroscience Division, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Oksana TatarinaCognitive Neuroscience Division, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA.

Funding

PREDICTORS OF SEVERITY IN ALZHEIMERS DISEASER01AG007370 · NIA · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI STERN, YAAKOV · 1989 to 2021
$16.6M
NIA NIH HHS R01 AG007370
6 · The paper itself

Abstract

introductionThe Predictors study was designed to predict the length of time to major disease outcomes in Alzheimer's disease (AD) patients. Here, we describe the development of a new, Predictors 3, cohort.

methodsPatients with prevalent or incident AD and individuals at-risk for developing AD were selected from the North Manhattan community and followed annually with instruments comparable to those used in the original two Predictors cohorts.

resultsThe original Predictors cohorts were clinic based and racially/ethnically homogenous (94% white, 6% black; 3% Hispanic). In contrast, the 274 elders in this cohort are community-based and ethnically diverse (39% white, 40% black, 21% other; 78% Hispanic). Confirming previous observations, psychotic features were associated with poorer function and mental status and extrapyramidal signs with poorer function. DISCUSSION: This new cohort will allow us to test observations made in our original clinic-based cohorts in patients that may be more representative of the general community.

Indexed as

Psychiatric Status Rating ScalesAgedAged, 80 and overAlzheimer DiseaseCognition DisordersCohort StudiesDepressionFemaleHumansMaleNeurologic ExaminationNeuropsychological TestsNew York CityPredictive Value of TestsSurveys and QuestionnairesADLCognitive functionExtrapyramidal signsMCIPharmacoeconomicsPrediction algorithmsPsychotic features

Identifiers

PMID27219818
PMCPMC5118195

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.