Evidence map›Paper›PMID 27219341›Full record

ArticleVaccine2016

The impact of implementing a demand forecasting system into a low-income country's supply chain.

Leslie E Mueller, Leila A Haidari, Angela R Wateska, Roslyn J Phillips, Michelle M Schmitz, Diana L Connor, Bryan A Norman, Shawn T Brown, Joel S Welling, Bruce Y Lee

Open access · greenAbstract read
In one paragraph

Article in Vaccine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Forecasting Demand for the Typhoid Conjugate Vaccine in Low- and Middle-income Countries.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Leslie E MuellerPublic Health Computational and Operations Research (PHICOR), Pittsburgh, PA, USA (formerly) and Baltimore, MD, USA (currently); Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Leila A HaidariPublic Health Computational and Operations Research (PHICOR), Pittsburgh, PA, USA (formerly) and Baltimore, MD, USA (currently); Pittsburgh Supercomputing Center (PSC), Pittsburgh, PA, USA.
Angela R WateskaPublic Health Computational and Operations Research (PHICOR), Pittsburgh, PA, USA (formerly) and Baltimore, MD, USA (currently).
Roslyn J PhillipsPublic Health Computational and Operations Research (PHICOR), Pittsburgh, PA, USA (formerly) and Baltimore, MD, USA (currently).
Michelle M SchmitzPublic Health Computational and Operations Research (PHICOR), Pittsburgh, PA, USA (formerly) and Baltimore, MD, USA (currently).
Diana L ConnorPublic Health Computational and Operations Research (PHICOR), Pittsburgh, PA, USA (formerly) and Baltimore, MD, USA (currently).
Bryan A NormanDepartment of Industrial Engineering, University of Pittsburgh, Pittsburgh, PA, USA.
Shawn T BrownPittsburgh Supercomputing Center (PSC), Pittsburgh, PA, USA.
Joel S WellingPittsburgh Supercomputing Center (PSC), Pittsburgh, PA, USA.
Bruce Y LeePublic Health Computational and Operations Research (PHICOR), Pittsburgh, PA, USA (formerly) and Baltimore, MD, USA (currently); Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address: brucelee@jhu.edu.
Pittsburgh Supercomputing Center · USJohns Hopkins University · USUniversity of Pittsburgh · US

Funding

MULTILEVEL SYSTEMS-ORIENTED CHILDHOOD OBESITY STUDY IN CHINAU54HD070725 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CURRIERO, FRANK · 2011 to 2016
$15.9M
MIDAS Informatics Services Group (ISG)U24GM110707 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ESPINO, JESSI U, WAGNER, MICHAEL MATTHEW · 2014 to 2018
$11.6M
Virtual Population Obesity Prevention (VPOP) Labs: Computational, Multi-Scale Models for Obesity SolutionsU01HD086861 · NICHD · JOHNS HOPKINS UNIVERSITY · PI LEE, BRUCE Y · 2015 to 2019
$2.8M
Regional Healthcare Ecosystem Analyst for Healthcare Associated InfectionsR01HS023317 · AHRQ · JOHNS HOPKINS UNIVERSITY · PI LEE, BRUCE Y · 2014 to 2014
$2.4M
AHRQ HHS R01 HS023317NICHD NIH HHS U01 HD086861NICHD NIH HHS U54 HD070725NIGMS NIH HHS U24 GM110707
6 · The paper itself

Abstract

objectiveTo evaluate the potential impact and value of applications (e.g. adjusting ordering levels, storage capacity, transportation capacity, distribution frequency) of data from demand forecasting systems implemented in a lower-income country's vaccine supply chain with different levels of population change to urban areas. MATERIALS AND

methodsUsing our software, HERMES, we generated a detailed discrete event simulation model of Niger's entire vaccine supply chain, including every refrigerator, freezer, transport, personnel, vaccine, cost, and location. We represented the introduction of a demand forecasting system to adjust vaccine ordering that could be implemented with increasing delivery frequencies and/or additions of cold chain equipment (storage and/or transportation) across the supply chain during varying degrees of population movement.

resultsImplementing demand forecasting system with increased storage and transport frequency increased the number of successfully administered vaccine doses and lowered the logistics cost per dose up to 34%. Implementing demand forecasting system without storage/transport increases actually decreased vaccine availability in certain circumstances. DISCUSSION: The potential maximum gains of a demand forecasting system may only be realized if the system is implemented to both augment the supply chain cold storage and transportation. Implementation may have some impact but, in certain circumstances, may hurt delivery. Therefore, implementation of demand forecasting systems with additional storage and transport may be the better approach. Significant decreases in the logistics cost per dose with more administered vaccines support investment in these forecasting systems.

conclusionDemand forecasting systems have the potential to greatly improve vaccine demand fulfilment, and decrease logistics cost/dose when implemented with storage and transportation increases. Simulation modeling can demonstrate the potential health and economic benefits of supply chain improvements.

Indexed as

PovertyComputer SimulationDrug StorageForecastingHealth Services Needs and DemandHumansModels, TheoreticalNigerRefrigerationTransportationVaccinesVaccinesHealth information systemsImmunizationInternational health

Identifiers

PMID27219341
PMCPMC4930702
OpenAlexW2401405858

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.