Evidence map›Paper›PMID 27219296›Full record

ArticleAmerican journal of industrial medicine2016

Respirable indium exposures, plasma indium, and respiratory health among indium-tin oxide (ITO) workers.

Kristin J Cummings, M Abbas Virji, Ji Young Park, Marcia L Stanton, Nicole T Edwards, Bruce C Trapnell, Brenna Carey, Aleksandr B Stefaniak, Kathleen Kreiss

Open access · greenAbstract read
In one paragraph

Article in American journal of industrial medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Elevated COAntioxidants (Basel, Switzerland) · 2022
    Article
  9. COFrontiers in plant science · 2022
    Article
  10. Article
  11. Article
  12. Low serum indium levels induce expression disorders of some inflammatory factors.International archives of occupational and environmental health · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. NIOSH's Respiratory Health Division: 50 years of science and service.Archives of environmental & occupational health · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Kristin J CummingsNational Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia.
M Abbas VirjiNational Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia.
Ji Young ParkNational Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia.
Marcia L StantonNational Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia.
Nicole T EdwardsNational Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia.
Bruce C TrapnellTranslational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Brenna CareyTranslational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Aleksandr B StefaniakNational Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia.
Kathleen KreissNational Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia.
Centers for Disease Control and Prevention · USNational Institute for Occupational Safety and Health · USCincinnati Children's Hospital Medical Center · USUniversity of Cincinnati · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundWorkers manufacturing indium-tin oxide (ITO) are at risk of elevated indium concentration in blood and indium lung disease, but relationships between respirable indium exposures and biomarkers of exposure and disease are unknown.

methodsFor 87 (93%) current ITO workers, we determined correlations between respirable and plasma indium and evaluated associations between exposures and health outcomes.

resultsCurrent respirable indium exposure ranged from 0.4 to 108 μg/m(3) and cumulative respirable indium exposure from 0.4 to 923 μg-yr/m(3) . Plasma indium better correlated with cumulative (rs  = 0.77) than current exposure (rs  = 0.54) overall and with tenure ≥1.9 years. Higher cumulative respirable indium exposures were associated with more dyspnea, lower spirometric parameters, and higher serum biomarkers of lung disease (KL-6 and SP-D), with significant effects starting at 22 μg-yr/m(3) , reached by 46% of participants.

conclusionsPlasma indium concentration reflected cumulative respirable indium exposure, which was associated with clinical, functional, and serum biomarkers of lung disease. Am. J. Ind. Med. 59:522-531, 2016. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

Indexed as

AdultAir Pollutants, OccupationalBiomarkersEnvironmental MonitoringHumansIndiumLung DiseasesMiddle AgedOccupational ExposureOccupationsSpirometryTin CompoundsAir Pollutants, OccupationalBiomarkersIndiumindium tin oxideTin Compoundscumulative exposureindium-tin oxideKL-6SP-Dspirometry

Identifiers

PMID27219296
PMCPMC4915590
OpenAlexW2404590692

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.