Evidence map›Paper›PMID 27219099›Full record

Trial reportAlcoholism, clinical and experimental research2016

Effect of Alcohol on Encoding and Consolidation of Memory for Alcohol-Related Images.

Jessica Weafer, David A Gallo, Harriet de Wit

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Alcoholism, clinical and experimental research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Neural correlates of inhibitory control are associated with stimulant-like effects of alcohol.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Trial
  2. Striatal activation to monetary reward is associated with alcohol reward sensitivity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Trial
  3. Trial
  4. Article
  5. Review
  6. Alcohol-Induced Retrograde Facilitation?Experimental psychology · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Intranasal Oxytocin Does Not Modulate Responses to Alcohol in Social Drinkers.Alcoholism, clinical and experimental research · 2018
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jessica WeaferDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois.
David A GalloDepartment of Psychology , University of Chicago, Chicago, Illinois.
Harriet de WitDepartment of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois.

Funding

Determinants of Drug Preference in Humans--Administrative SupplementR01DA002812 · NIDA · UNIVERSITY OF CHICAGO · PI DE WIT, HARRIET · 1985 to 2024
$10.6M
Memory effects of stimulant drugs in humansR21DA031796 · NIDA · UNIVERSITY OF CHICAGO · PI DE WIT, HARRIET · 2012 to 2013
$411k
NIDA NIH HHS R01 DA002812NIDA NIH HHS R21 DA031796
6 · The paper itself

Abstract

backgroundDrug and alcohol abusers develop strong memories for drug-related stimuli. Preclinical studies suggest that such memories are a result of drug actions on reward pathways, which facilitate learning about drug-related stimuli. However, few controlled studies have investigated how drugs affect memory for drug-related stimuli in humans.

methodsThe current study examined the direct effect of alcohol on memory for images of alcohol-related or neutral beverages. Participants received alcohol (0.8 g/kg) either before viewing visual images (encoding condition; n = 20) or immediately after viewing them (consolidation condition; n = 20). A third group received placebo both before and after viewing the images (control condition; n = 19). Memory retrieval was tested exactly 48 hours later, in a drug-free state.

resultsAlcohol impaired memory in the encoding condition and enhanced memory in the consolidation condition, but these effects did not differ for alcohol-related and neutral beverage stimuli. However, in the encoding condition, participants who experienced greater alcohol-induced stimulation exhibited better memory for alcohol-related, but not neutral beverage stimuli.

conclusionsThese findings suggest that individual differences in sensitivity to the positive, rewarding effects of alcohol are associated with greater propensity to remember alcohol-related stimuli encountered while intoxicated. As such, stimulant responders may form stronger memory associations with alcohol-related stimuli, which might then influence their drinking behavior.

Indexed as

BeveragesBreath TestsCuesDouble-Blind MethodEthanolFemaleHumansMaleMemory ConsolidationMental RecallPhotic StimulationRecognition, PsychologyYoung AdultEthanolAlcohol StimuliConsolidationEncodingMemoryStimulation

Identifiers

PMID27219099
PMCPMC4930409

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.