Evidence map›Paper›PMID 27219068›Full record

ArticleNeuropsychological rehabilitation2018

Personalised treatment for cognitive dysfunction in individuals with schizophrenia spectrum disorders.

Alice Medalia, Alice M Saperstein, Marie C Hansen, Seonjoo Lee

Registry-linked trialAbstract read
In one paragraph

Article in Neuropsychological rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04040829 (Cognitive Remediation and Supported Education in Psychotic Disorders), which is not on this map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04040829 naterminatednot on this mapstarted 2021, after this paper: background citation

Cognitive Remediation and Supported Education in Psychotic Disorders: a Randomized Controlled Trial on the Efficacy and the Best Predictors of Academic Functioning

TypeinterventionalSponsorCentre de Recherche de l'Institut Universitaire en Santé Mentale de QuébecRan2021 to 2023Enrolled9ConditionsPsychotic DisordersArmsCognitive remediation therapy (CR), Supported education (SE), Treatment as usual (TAU)
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alice Medaliaa Department of Psychiatry , Columbia University , New York , USA.
Alice M Sapersteinb Department of Psychology , Long Island University , Brooklyn , USA.
Marie C Hansena Department of Psychiatry , Columbia University , New York , USA.
Seonjoo Leea Department of Psychiatry , Columbia University , New York , USA.

Funding

Personalized and Scalable Cognitive Remediation ApproachesR34MH100317 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MEDALIA, ALICE · 2013 to 2015
$735k
NIMH NIH HHS R34 MH100317
6 · The paper itself

Abstract

Cognitive deficits are a well-recognised issue for individuals diagnosed with schizophrenia spectrum disorders. Despite positive group findings for the use of cognitive remediation (CR) interventions, there are substantial individual differences in response to treatment. In addition, the aggregate CR literature reports low moderate effect sizes for cognitive and functional outcomes. Based on personalised medicine theory, this paper uses extant CR literature to examine the individual characteristics determined to predict treatment response. These characteristics, which fall into the broad categories of cognitive, psychological, and biological can be used as tailoring variables to personalise CR to an individual's unique profile. Personalisation through the use of these tailoring variables has the potential to improve the delivery of CR to maximise treatment outcomes.

Indexed as

Cognitive Behavioral TherapyAttentionCognitive DysfunctionHumansMotivationPrecision MedicineSchizophreniaSchizophrenic PsychologyTreatment OutcomeCognitive remediationneurocognitionpersonalised treatmentschizophrenia

Identifiers

PMID27219068
PMCPMC5951177

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.