Evidence map›Paper›PMID 27218461›Full record

ArticleOrganic letters2016

[3 + 2]-Cycloadditions of Azomethine Imines and Ynolates.

Sarah E Winterton, Joseph M Ready

Abstract read
In one paragraph

Article in Organic letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sarah E WintertonDepartment of Biochemistry, Division of Chemistry, UT Southwestern Medical Center , 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, United States.
Joseph M ReadyDepartment of Biochemistry, Division of Chemistry, UT Southwestern Medical Center , 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038, United States.

Funding

Synthesis and Evaluation of Biologically Active Natural ProductsR01GM102403 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI READY, JOSEPH M · 2013 to 2016
$1.2M
NIGMS NIH HHS R01 GM102403
6 · The paper itself

Abstract

A novel [3 + 2]-cycloaddition between azomethine imines and lithium ynolates is described to synthesize bicyclic pyrazolidinones. These bicyclic pyrazolidinones are versatile intermediates to form β-amino acids and monocyclic pyrazolidinones. High diastereoselectivity and stereospecificity allow access to optically active products.

Indexed as

AlkynesAzo CompoundsCatalysisCycloaddition ReactionIminesMolecular StructurePyrazolesStereoisomerismThiosemicarbazonesAlkynesAzo CompoundsazomethineIminesPyrazolesThiosemicarbazones

Identifiers

PMID27218461
PMCPMC4961353

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.