ArticleEcology and evolution2016
Meta-analysis indicates that oxidative stress is both a constraint on and a cost of growth.
Article in Ecology and evolution, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 114 citations in OpenAlex.
- Sex-Specific Yolk Allocation Revisited: A Test in Starlings and a Review of Evidence in Birds.Integrative organismal biology (Oxford, England) · 2026Article
- Female Starlings With Experimentally Impaired Pre-Laying Condition Produce Smaller But Vitamin A Richer Eggs.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2025Article
- Antioxidant Potential of Pollen Polyphenols in Mitigating Environmental Stress in Honeybees (Antioxidants (Basel, Switzerland) · 2025Review
- Fluctuating salinity during development impacts fish life histories.The Journal of animal ecology · 2025Article
- Growth rate is associated with reduced oxidative stress and this effect is modulated by the degree of social dominance in males of an African cichlid fish.Comparative biochemistry and physiology. Part A, Molecular & integrative physiology · 2025Article
- Life at new extremes: Integrating stress physiology and the bio-exposome in the Anthropocene.Annals of the New York Academy of Sciences · 2025Review
- Does colour-morph variation in metabolic physiology and oxidative stress match morph-specific life-history strategies?Oecologia · 2025Article
- Linking warmer nest temperatures to reduced body size in seabird nestlings: possible mitochondrial bioenergetic and proteomic mechanisms.The Journal of experimental biology · 2025Article
- Depressed nestling growth during exposure to smoke from distant wildfires.Scientific reports · 2025Article
- Oxidative Stress in Children and Adolescents: Insights Into Human Biology.American journal of human biology : the official journal of the Human Biology Council · 2025Review
- INTERACTIVE EFFECTS OF INCREASED NESTBOX TEMPERATURE AND VITAMIN E ON NESTLING GROWTH ARE ATTENUATED BY PLASTICITY IN FEMALE INCUBATION EFFORT.Ethology : formerly Zeitschrift fur Tierpsychologie · 2024Article
- Sex and early-life conditions shape telomere dynamics in an ectotherm.The Journal of experimental biology · 2024Article
- Seasonal changes in diet, immune function, and oxidative stress in three passerines inhabiting a Mediterranean climate.Oecologia · 2023Article
- Prenatal thyroid hormones accelerate postnatal growth and telomere shortening in wild great tits.The Journal of experimental biology · 2023Article
- Ageing across the great divide: tissue transformation, organismal growth and temperature shape telomere dynamics through the metamorphic transition.Proceedings. Biological sciences · 2023Article
- Does pre-spawning catch and release angling affect offspring telomere dynamics in Atlantic salmon?Conservation physiology · 2023Article
- Habitat restoration weakens negative environmental effects on telomere dynamics.Molecular ecology · 2022Article
- Early life parameters and personality affect oxidative status during adulthood in an altricial rodent.Physiological reports · 2022Article
- Flexible growth and body mass predict physiological condition at fledging in the synchronously breeding European starling,Royal Society open science · 2022Article
- Metabolomic Predictors of Dysglycemia in Two U.S. Youth Cohorts.Metabolites · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress (OS) as a proximate mechanism for life-history trade-offs is widespread in the literature. One such resource allocation trade-off involves growth rate, and theory suggests that OS might act as both a constraint on and a cost of growth, yet studies investigating this have produced conflicting results. Here, we use meta-analysis to investigate whether increased OS levels impact on growth (OS as a constraint on growth) and whether greater growth rates can increase OS (OS as a cost of growth). The role of OS as a constraint on growth was supported by the meta-analysis. Greater OS, in terms of either increased damage or reduced levels of antioxidants, was associated with reduced growth although the effect depended on the experimental manipulation used. Our results also support an oxidative cost of growth, at least in terms of increased oxidative damage, although faster growth was not associated with a change in antioxidant levels. These findings that OS can act as a constraint on growth support theoretical links between OS and animal life histories and provide evidence for a growth-self-maintenance trade-off. Furthermore, the apparent oxidative costs of growth imply individuals cannot alter this trade-off when faced with enhanced growth. We offer a starting platform for future research and recommend the use of oxidative damage biomarkers in nonlethal tissue to investigate the growth-OS relationship further.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.