Evidence map›Paper›PMID 27217730›Full record

ArticleClinical interventions in aging2016

Validation of three tools for identifying painful new osteoporotic vertebral fractures in older Chinese men: bone mineral density, Osteoporosis Self-Assessment Tool for Asians, and fracture risk assessment tool.

JiSheng Lin, Yong Yang, Qi Fei, XiaoDong Zhang, Zhao Ma, Qi Wang, JinJun Li, Dong Li, Qian Meng, BingQiang Wang

Open access · goldAbstract readValidation Study
In one paragraph

Article in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Combining OSTA and BMR to predict osteoporosis in Chinese population.Journal of orthopaedic surgery and research · 2024
    Article
  6. Article
  7. Article
  8. Prevalence and Risk Factors of Osteoporosis in a Chinese Population: A Cross-Sectional Study in Xi'an, Shaanxi Province, China.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Performance of Osteoporosis Self-Assessment Tool (OST) in Predicting Osteoporosis-A Review.International journal of environmental research and public health · 2018
    Review
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  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

JiSheng LinDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Yong YangDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Qi FeiDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
XiaoDong ZhangDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Zhao MaDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Qi WangDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
JinJun LiDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Dong LiDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Qian MengDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
BingQiang WangDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, People's Republic of China.
Capital Medical University · CNBeijing Friendship Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis cross-sectional study compared three tools for predicting painful new osteoporotic vertebral fractures (PNOVFs) in older Chinese men: bone mineral density (BMD), the Osteoporosis Self-Assessment Tool for Asians (OSTA), and the World Health Organization fracture risk assessment tool (FRAX) (without BMD).

methodsMen aged ≥50 years were apportioned to a group for men with fractures who had undergone percutaneous vertebroplasty (n=111), or a control group of healthy men (n=385). Fractures were verified on X-ray and magnetic resonance imaging. BMD T-scores were determined by dual energy X-ray absorptiometry. Diagnosis of osteoporosis was determined by a BMD T-score of ≤2.5 standard deviations below the average for a young adult at peak bone density at the femoral neck, total hip, or L1-L4. Demographic and clinical risk factor data were self-reported through a questionnaire. BMD, OSTA, and FRAX scores were assessed for identifying PNOVFs via receiver-operating characteristic (ROC) curves. Optimal cutoff points, sensitivity, specificity, and areas under the ROC curves (AUCs) were determined.

resultsBetween the men with fractures and the control group, there were significant differences in BMD T-scores (at femoral neck, total hip, and L1-L4), and OSTA and FRAX scores. In those with fractures, only 53.15% satisfied the criteria for osteoporosis. Compared to BMD or OSTA, the FRAX score had the best predictive value for PNOVFs: the AUC of the FRAX score (cutoff =2.9%) was 0.738, and the sensitivity and specificity were 82% and 62%, respectively.

conclusionFRAX may be a valuable tool for identifying PNOVFs in older Chinese men.

Indexed as

Bone DensitySelf-AssessmentAbsorptiometry, PhotonAgedAged, 80 and overArea Under CurveCase-Control StudiesChinaCross-Sectional StudiesHumansMagnetic Resonance ImagingMaleMiddle AgedOsteoporosisOsteoporotic FracturesPainbone mineral densityFRAXmaleOSTAosteoporosisvertebral fracture

Identifiers

PMID27217730
PMCPMC4853018
OpenAlexW2342783171

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.