Evidence map›Paper›PMID 27217697›Full record

ReviewWorld journal of gastroenterology2016

Auto immune hepatitis.

Nicole Mf van Gerven, Ynto S de Boer, Chris Jj Mulder, Carin Mj van Nieuwkerk, Gerd Bouma

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Histology and histopathology · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Autoimmune Hepatitis Leading to Liver Cirrhosis: A Case Report.JNMA; journal of the Nepal Medical Association · 2022
    Article
  16. Article
  17. Review
  18. Article
  19. Early Predictors of Short-Term Prognosis in Acute and Acute Severe Autoimmune Hepatitis.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2020
    Article
  20. Frequency of OBI among Patients with Autoimmune Hepatitis.Asian Pacific journal of cancer prevention : APJCP · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nicole Mf van GervenNicole MF van Gerven, Ynto S de Boer, Chris JJ Mulder, Carin MJ van Nieuwkerk, Gerd Bouma, Department of Gastroenterology and Hepatology, Vu University Medical Centre, 1081 HV, Amsterdam, The Netherlands.
Ynto S de BoerNicole MF van Gerven, Ynto S de Boer, Chris JJ Mulder, Carin MJ van Nieuwkerk, Gerd Bouma, Department of Gastroenterology and Hepatology, Vu University Medical Centre, 1081 HV, Amsterdam, The Netherlands.
Chris Jj MulderNicole MF van Gerven, Ynto S de Boer, Chris JJ Mulder, Carin MJ van Nieuwkerk, Gerd Bouma, Department of Gastroenterology and Hepatology, Vu University Medical Centre, 1081 HV, Amsterdam, The Netherlands.
Carin Mj van NieuwkerkNicole MF van Gerven, Ynto S de Boer, Chris JJ Mulder, Carin MJ van Nieuwkerk, Gerd Bouma, Department of Gastroenterology and Hepatology, Vu University Medical Centre, 1081 HV, Amsterdam, The Netherlands.
Gerd BoumaNicole MF van Gerven, Ynto S de Boer, Chris JJ Mulder, Carin MJ van Nieuwkerk, Gerd Bouma, Department of Gastroenterology and Hepatology, Vu University Medical Centre, 1081 HV, Amsterdam, The Netherlands.
Amsterdam UMC Location VUmc · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To provide an update of the latest trends in epidemiology, clinical course, diagnostics, complications and treatment of auto immune hepatitis (AIH). A search of the MEDLINE database was performed using the search terms: "auto immune hepatitis", "clinical presentation", "symptoms", "signs", "diagnosis", "auto antibodies", "laboratory values", "serology", "histopathology", "histology", "genetics", "HLA genes", "non-HLA genes", "environment", "epidemiology", "prevalence", "incidence", "demographics", "complications", "HCC", "PBC", "PSC", "corticosteroid", "therapy", "treatment", "alternative treatment". English-language full-text articles and abstracts were considered. Articles included reviews, meta-analysis, prospective retrospective studies. No publication date restrictions were applied. AIH is an immune meditated progressive inflammatory liver disease that predominantly affects middle-aged females but may affect people of all ages. The clinical spectrum of AIH is wide, ranging from absent or mild symptoms to fulminant hepatic failure. The aetiology of AIH is still unknown, but is believed to occur as the consequence of an aberrant immune response towards an un-known trigger in a genetically susceptible host. In the absence of a gold standard, diagnosis is based on the combination of clinical, biochemical and histopathological criteria. Immunosuppressive treatment has been the cornerstone of treatment since the earliest description of the disease in 1950 by Waldenström. Such treatment is often successful at inducing remission and generally leads to normal life expectancy. Nevertheless, there remain significant areas of unmet aetiological a clinical needs including fundamental insight in disease pathogenesis, optimal therapy, duration of treatment and treatment alternatives in those patients unresponsive to standard treatment regimens.

Indexed as

Hepatitis, AutoimmuneAnimalsDisease ProgressionGenetic Predisposition to DiseaseHumansImmunosuppressive AgentsPredictive Value of TestsRecurrenceRemission InductionRisk FactorsSeverity of Illness IndexTreatment OutcomeImmunosuppressive AgentsAuto immune hepatitisDiagnosisEpidemiologyLiverTreatment

Identifiers

PMID27217697
PMCPMC4870072
OpenAlexW2401798088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.