Evidence map›Paper›PMID 27217381›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2017

Evidence that adenosine contributes to Leao's spreading depression in vivo.

Britta E Lindquist, C William Shuttleworth

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  8. Synaptic ZnNeurobiology of disease · 2024
    Article
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  11. Synaptic ZnbioRxiv : the preprint server for biology · 2023
    Article
  12. Review
  13. Article
  14. Article
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  16. Article
  17. Migraine and Sleep-An Unexplained Association?International journal of molecular sciences · 2021
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Britta E LindquistDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA.
C William ShuttleworthDepartment of Neurosciences, University of New Mexico School of Medicine, Albuquerque, NM, USA.
University of New Mexico · US

Funding

University of New Mexico (UNM) Center for Brain Recovery and RepairP20GM109089 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI SHUTTLEWORTH, CLAUDE W · 2015 to 2024
$22.7M
Spreading Depolarizations and Post-Ischemic InjuryR01NS051288 · NINDS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI SHUTTLEWORTH, CLAUDE W · 2006 to 2014
$2.6M
NIGMS NIH HHS P20 GM109089NINDS NIH HHS R01 NS051288
6 · The paper itself

Abstract

Leao's spreading depression of cortical activity is a propagating silencing of neuronal activity resulting from spreading depolarization (SD). We evaluated the contributions of action potential (AP) failure and adenosine A

Indexed as

Action PotentialsAdenosineAdenosine A1 Receptor AntagonistsAnimalsCortical Spreading DepressionElectrocorticographyFemaleMaleMice, Inbred C57BLReceptor, Adenosine A1Synaptic PotentialsAdenosineAdenosine A1 Receptor AntagonistsReceptor, Adenosine A1adenosineenergy metabolismevoked potentialsSpreading depressionsynapses/dendrites

Identifiers

PMID27217381
PMCPMC5435284
OpenAlexW2400545047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.