Trial reportClinical infectious diseases : an official publication of the Infectious Diseases Society of America2016
A Randomized Trial to Test a Peer Mentor Intervention to Improve Outcomes in Persons Hospitalized With HIV Infection.
Trial report in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01103856 (Test of an Intervention to Improve HIV Care), which is not on this map. Cited by 40 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Test of an Intervention to Improve HIV Care
Who cites it
40 citing papers in PubMed, 9 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Antiretroviral Therapy Adherence Interventions in the Era of Universal Test and Treat: A Hybrid Systematic-Narrative Literature Review of Global Evidence.AIDS and behavior · 2026Pooled it
- Strategies for improving linkage to HIV care after hospital discharge among adults living with HIV in low- and middle-income countries: a systematic review.BMC public health · 2025Pooled it
- Evidence from high-income countries on the effectiveness of psychosocial interventions to improve mental health, wellbeing and quality of life for adults living with HIV: a systematic review and meta-analysis.Journal of the International AIDS Society · 2025Pooled it
- Psychosocial Interventions to Promote Undetectable HIV Viral Loads: A Systematic Review of Randomized Clinical Trials.AIDS and behavior · 2022Pooled it
- The effectiveness of peer-support for people living with HIV: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Interventions to improve self-management of adults living with HIV on Antiretroviral Therapy: A systematic review.PloS one · 2020Pooled it
- A need for implementation science to optimise the use of evidence-based interventions in HIV care: A systematic literature review.PloS one · 2019Pooled it
- Guideline
- Pooled it
- Next-Day HIV Viral Load Test Result and Linkage to Care Among Persons Living With or at Risk of HIV: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Initiation of Antiretroviral Therapy in the Hospital Is Associated With Linkage to Human Immunodeficiency Virus (HIV) Care for Persons Living With HIV and Substance Use Disorder.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Trial
- Peer support to maintain psychological wellbeing in people with advanced cancer: findings from a feasibility study for a randomised controlled trial.BMC palliative care · 2020Trial
- The Association of Unmet Needs With Subsequent Retention in Care and HIV Suppression Among Hospitalized Patients With HIV Who Are Out of Care.Journal of acquired immune deficiency syndromes (1999) · 2019Trial
- A Randomized Controlled Trial of a Text Messaging Intervention to Promote Virologic Suppression and Retention in Care in an Urban Safety-Net Human Immunodeficiency Virus Clinic: The Connect4Care Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Trial
- Effectiveness of a Peer Navigation Intervention to Sustain Viral Suppression Among HIV-Positive Men and Transgender Women Released From Jail: The LINK LA Randomized Clinical Trial.JAMA internal medicine · 2018Trial
- Effects of social support interventions on social, physical and mental health outcomes: a scoping review.BMJ public health · 2026Article
- Conceptualisation and operationalisation of social support in health interventions: a scoping review.BMJ public health · 2026Article
- Developing and evaluating a young adult peer mentor training program.Health care transitions · 2026Article
- Ensuring effective transitions in care for hospitalized people living with HIV.Frontiers in public health · 2026Review
- Interventions to Support People With HIV Following Hospital Discharge: A Systematic Review.Open forum infectious diseases · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundFew interventions have been shown to improve retention in human immunodeficiency virus (HIV) care, and none have targeted the hospitalized patient. Peer mentoring has not been rigorously tested.
methodsWe conducted a randomized, controlled clinical trial of a peer mentoring intervention. Eligible adults were hospitalized and were either newly diagnosed with HIV infection or out of care. The intervention included 2 in-person sessions with a volunteer peer mentor while hospitalized, followed by 5 phone calls in the 10 weeks after discharge. The control intervention provided didactic sessions on avoiding HIV transmission on the same schedule. The primary outcome was a composite of retention in care (completed HIV primary care visits within 30 days and between 31 and 180 days after discharge) and viral load (VL) improvement (≥1 log10 decline) 6 months after discharge.
resultsWe enrolled 460 participants in 3 years; 417 were in the modified intent-to-treat analysis. The median age was 42 years; 74% were male; and 67% were non-Hispanic black. Baseline characteristics did not differ between the randomized groups. Twenty-eight percent of the participants in both arms met the primary outcome (P = .94). There were no differences in prespecified secondary outcomes, including retention in care and VL change. Post hoc analyses indicated interactions between the intervention and length of hospitalization and between the intervention and receipt of linkage services before discharge.
conclusionsPeer mentoring did not increase reengagement in outpatient HIV care among hospitalized, out-of-care persons. More intense and system-focused interventions warrant further study. CLINICAL TRIALS REGISTRATION: NCT01103856.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.