ArticleLab on a chip2016
3D-printing of transparent bio-microfluidic devices in PEG-DA.
Article in Lab on a chip, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
102 citing papers in PubMed, 277 citations in OpenAlex.
- Defining Operational Limits of Low-Cost MSLA 3D Printing for Microfluidic Systems: Resin Performance, Cell Compatibility, and Fluid Dynamics.ACS omega · 2026Article
- Biocompatible designated Resin-3D-printed polymers exhibit reproductive toxicity prevented by Parylene-C.bioRxiv : the preprint server for biology · 2026Article
- Enhancing the Hemocompatibility of 3D-Printable Silicone Elastomers for Artificial Lung Applications.Langmuir : the ACS journal of surfaces and colloids · 2026Article
- Additive Manufacturing of Molecular Architecture Encoded Stretchable Polyethylene Glycol Hydrogels and Elastomers.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Fast multi-resolution 3D printing of microfluidics: enabling 2 μm channels and ultra-compact mixers.Microsystems & nanoengineering · 2026Article
- Oxidation-degradable resins for 3D-printing of cell-responsive biomaterials.Advanced functional materials · 2025Article
- Rigor & Reproducibility: pH Adjustments of Papain with L-Cysteine Dissociation Solutions and Cell Media Using Phenol Red Spectrophotometry.Biosensors · 2025Article
- Advancing Modular Microfluidics: Stereolithographic 3D Printing of Reconfigurable Connectors for Bioanalytical Applications.International journal of bioprinting · 2025Article
- Article
- Process Study on 3D Printing of Polymethyl Methacrylate Microfluidic Chips for Chemical Engineering.Micromachines · 2025Article
- From Soft Lithography to 3D Printing: Current Status and Future of Microfluidic Device Fabrication.Polymers · 2025Review
- Simple-Flow: A 3D-Printed Multiwell Flow Plate to Coculture Primary Human Lung Cells at the Air-Liquid Interface.ACS biomaterials science & engineering · 2025Article
- Fused Deposition Modeling of Chemically Resistant Microfluidic Chips in Polyvinylidene Fluoride.Micromachines · 2024Article
- Towards a 3D-Printed Millifluidic Device for Investigating Cellular Processes.Micromachines · 2024Article
- A virtual visualization method for improving the manufacturing accuracy based VPP 3D printers.Heliyon · 2024Article
- Dimensional Accuracy of Different Three-Dimensional Printing Models as a Function of Varying the Printing Parameters.Materials (Basel, Switzerland) · 2024Article
- High-Scale 3D-Bioprinting Platform for the Automated Production of Vascularized Organs-on-a-Chip.Advanced healthcare materials · 2024Article
- An economical in-class sticker microfluidic activity develops student expertise in microscale physics and device manufacturing.Lab on a chip · 2024Article
- Impact of Beam Shape on Print Accuracy in Digital Light Processing Additive Manufacture.3D printing and additive manufacturing · 2024Article
- Auto-amplification and spatial propagation of neutrophil extracellular traps.Communications biology · 2024Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 5 countries.
Funding
Abstract
The vast majority of microfluidic systems are molded in poly(dimethylsiloxane) (PDMS) by soft lithography due to the favorable properties of PDMS: biocompatible, elastomeric, transparent, gas-permeable, inexpensive, and copyright-free. However, PDMS molding involves tedious manual labor, which makes PDMS devices prone to assembly failures and difficult to disseminate to research and clinical settings. Furthermore, the fabrication procedures limit the 3D complexity of the devices to layered designs. Stereolithography (SL), a form of 3D-printing, has recently attracted attention as a way to customize the fabrication of biomedical devices due to its automated, assembly-free 3D fabrication, rapidly decreasing costs, and fast-improving resolution and throughput. However, existing SL resins are not biocompatible and patterning transparent resins at high resolution remains difficult. Here we report procedures for the preparation and patterning of a transparent resin based on low-MW poly(ethylene glycol) diacrylate (MW 250) (PEG-DA-250). The 3D-printed devices are highly transparent and cells can be cultured on PEG-DA-250 prints for several days. This biocompatible SL resin and printing process solves some of the main drawbacks of 3D-printed microfluidic devices: biocompatibility and transparency. In addition, it should also enable the production of non-microfluidic biomedical devices.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.