ArticleTrends in biochemical sciences2016
Cobalamin's (Vitamin B12) Surprising Function as a Photoreceptor.
Article in Trends in biochemical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 54 citations in OpenAlex.
- Integrated structural dynamics uncover a new BNature · 2026Article
- Protein design accelerates the development and application of optogenetic tools.Computational and structural biotechnology journal · 2025Review
- Photocobilins integrate BNature communications · 2024Article
- The blue light-dependent LOV-protein LdaP ofFrontiers in microbiology · 2024Article
- Redox driven BNature communications · 2023Article
- Residue alterations within a conserved hydrophobic pocket influence light, oxygen, voltage photoreceptor dark recovery.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2023Article
- Optophysiology: Illuminating cell physiology with optogenetics.Physiological reviews · 2022Review
- Structural Analyses of CrtJ and Its BMicroorganisms · 2022Article
- Antivitamins BChemistry (Weinheim an der Bergstrasse, Germany) · 2020Review
- Microbiome and Functional Analysis of a Traditional Food Process: Isolation of a Novel Species (Frontiers in microbiology · 2020Article
- Metagenomic and chemical characterization of soil cobalamin production.The ISME journal · 2020Article
- Photosensing and quorum sensing are integrated to control Pseudomonas aeruginosa collective behaviors.PLoS biology · 2019Article
- Exposure to Broad-Spectrum Visible Light Causes Major Transcriptomic Changes inApplied and environmental microbiology · 2019Article
- Differing isoforms of the cobalamin binding photoreceptor AerR oppositely regulate photosystem expression.eLife · 2018Article
- A Cobalamin Activity-Based Probe Enables Microbial Cell Growth and Finds New Cobalamin-Protein Interactions across Domains.Applied and environmental microbiology · 2018Article
- A New Facet of Vitamin BAnnual review of biochemistry · 2017Review
- The Vitamin BmBio · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Cobalamin (Vitamin B12) is an adenosyl- or methyl-donating cofactor for many enzymes, yet many proteins with unknown or nonenzymatic function also contain B12-binding domains. Recent studies show that light excitation energy can promote covalent linkage of B12 to transcription factors with this linkage, affecting gene expression. Thus, B12 now has a newly described regulatory function. Here, our bioinformatics analysis reveals other transcription factors, photoreceptors, kinases, and oxygen sensors that harbor a B12-binding domain that could also regulate activity in response to light absorption.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.