ReviewDrugs & aging2016
Optimising Inhaled Pharmacotherapy for Elderly Patients with Chronic Obstructive Pulmonary Disease: The Importance of Delivery Devices.
Review in Drugs & aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Effect of fracture risk in inhaled corticosteroids in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis.BMC pulmonary medicine · 2023Pooled it
- Critical inhaler errors in asthma and COPD: a systematic review of impact on health outcomes.Respiratory research · 2018Pooled it
- Correct use and ease-of-use of placebo ELLIPTA dry-powder inhaler in adult patients with chronic obstructive pulmonary disease.PloS one · 2022Trial
- Comparison of peak inspiratory flow rate via the Breezhaler®, Ellipta® and HandiHaler® dry powder inhalers in patients with moderate to very severe COPD: a randomized cross-over trial.BMC pulmonary medicine · 2018Trial
- Inhaler mastery and retention after stepwise training in cognitively impaired older COPD.ERJ open research · 2026Article
- A Personalised 3D-Printed Dental Plaque Removal Mouthguard for Older Adults.International dental journal · 2023Article
- Cognitive impairment according to Montreal Cognitive Assessment independently predicts the ability of chronic obstructive pulmonary disease patients to maintain proper inhaler technique.BMC pulmonary medicine · 2023Article
- Relationship between Peak Inspiratory Flow and Patient and Disease Characteristics in Individuals with COPD-A Systematic Scoping Review.Biomedicines · 2022Article
- Individual trajectory-based care for COPD: getting closer, but not there yet.ERJ open research · 2021Review
- Treating COPD Patients with Inhaled Medications in the Era of COVID-19 and Beyond: Options and Rationales for Patients at Home.International journal of chronic obstructive pulmonary disease · 2021Review
- Optimizing Medication Management During the COVID-19 Pandemic: An Implementation Guide for Post-Acute and Long-Term Care.Journal of the American Geriatrics Society · 2020Article
- Incorporating the Environmental Impact into a Budget Impact Analysis: The Example of Adopting RESPIMATApplied health economics and health policy · 2020Article
- Inhaler Devices in a Geriatric Patient Population: A Prospective Cross-Sectional Study on Patient Preferences.Patient preference and adherence · 2020Article
- A Budget Impact Model to Estimate the Environmental Impact of Adopting RESPIMATAdvances in therapy · 2019Article
- Patients' usability of seven most used dry-powder inhalers in COPD.Multidisciplinary respiratory medicine · 2019Article
- Lipid-based pulmonary delivery system: a review and future considerations of formulation strategies and limitations.Drug delivery and translational research · 2018Review
- Continued Innovation in Respiratory Care: The Importance of Inhaler Devices.Tuberculosis and respiratory diseases · 2018Review
- Spacer devices for inhaled therapy: why use them, and how?ERJ open research · 2018Review
- Maintenance inhaler preference, attribute importance, and satisfaction in prescribing physicians and patients with asthma, COPD, or asthma-COPD overlap syndrome consulting for routine care.International journal of chronic obstructive pulmonary disease · 2018Article
- Routine Use of Budesonide/Formoterol Fixed Dose Combination in Elderly Asthmatic Patients: Practical Considerations.Drugs & aging · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic obstructive pulmonary disease (COPD) is common in older people. Inhaled medications are the mainstay of pharmacological treatment of COPD, and are typically administered by handheld inhalers, such as pressurised metered-dose inhalers and dry powder inhalers, or by nebulisers. For each of the three major categories of aerosol delivery devices, several new inhalers have recently been launched, each with their own particularities, advantages and disadvantages. Consequently, broader availability of new drug-device combinations will increase prescription opportunities. Despite this, however, there is limited guidance available in published guidelines on the choice of inhalers, and still less consideration is given to elderly patients with COPD. The aim of this article is to provide a guide for healthcare professionals on device selection and factors to be considered for effective inhaled drug delivery in elderly COPD patients, including device factors (device type and complexity of use), patient factors (inspiratory capabilities, manual dexterity and hand strength, cognitive ability, co-morbidities) and considerations for healthcare professionals (proper education of patients in device use).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.