Evidence map›Paper›PMID 27216257›Full record

ArticleThe Journal of cell biology2016

Division of labor in the growth cone by DSCR1.

Timothy S Catlett, Timothy M Gomez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of cell biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Timothy S CatlettDepartment of Neuroscience, University of Wisconsin, Madison, WI 53706 Cell and Molecular Biology Training Program, University of Wisconsin, Madison, WI 53706.
Timothy M GomezDepartment of Neuroscience, University of Wisconsin, Madison, WI 53706 Cell and Molecular Biology Training Program, University of Wisconsin, Madison, WI 53706 tmgomez@wisc.edu.

Funding

GRADUATE TRAINING IN MOLECULAR BIOSCIENCEST32GM007215 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HULL, CHRISTINA M · 1985 to 2018
$22.5M
Molecular mechanisms of growth cone invasionR01NS099405 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI GOMEZ, TIMOTHY M · 2016 to 2019
$1.4M
Modeling Neural Development Using Human iPSCs from TSC PatientsR21NS088477 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI GOMEZ, TIMOTHY M · 2014 to 2015
$414k
Regulation of Axon Guidance by Second MessengerR56NS041564 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI GOMEZ, TIMOTHY M · 2015 to 2015
$374k
NIGMS NIH HHS T32 GM007215NINDS NIH HHS R01 NS099405NINDS NIH HHS R21 NS088477NINDS NIH HHS R56 NS041564
6 · The paper itself

Abstract

Local protein synthesis directs growth cone turning of nascent axons, but mechanisms governing this process within compact, largely autonomous microenvironments remain poorly understood. In this issue, Wang et al. (2016. J. Cell Biol http://dx.doi.org/10.1083/jcb.201510107) demonstrate that the calcineurin regulator Down syndrome critical region 1 protein modulates both basal neurite outgrowth and growth cone turning.

Indexed as

CalcineurinCells, CulturedDNA-Binding ProteinsGrowth ConesHumansIntracellular Signaling Peptides and ProteinsMuscle ProteinsCalcineurinDNA-Binding ProteinsIntracellular Signaling Peptides and ProteinsMuscle ProteinsRCAN1 protein, human

Identifiers

PMID27216257
PMCPMC4878096

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.