ReviewNeuroscience and biobehavioral reviews2016
Generalized CNS arousal: An elementary force within the vertebrate nervous system.
Review in Neuroscience and biobehavioral reviews, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 70 citations in OpenAlex.
- Developing Context-Appropriate Emotions: Longitudinal Changes in Emotion Reactivity and Emotion Regulation From 6 to 12 Months.Developmental science · 2026Article
- Modeling Emotional Arousal With Turbulence Measured by EEG.Psychophysiology · 2025Article
- Stress, hypothalamic-pituitary-adrenal axis, hypothalamic-pituitary-gonadal axis, and aggression.Metabolic brain disease · 2024Review
- Arousal and the modulation of sensory experience: evidence from food-related emotions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- Astrocytes in Pain Perception: A Systems Neuroscience Approach.Advances in neurobiology · 2024Review
- Cognitive-Affective Functions of the Cerebellum.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Investigating the effectiveness of immersive VR skill training and its link to physiological arousal.Virtual reality · 2023Article
- Vocal communication is tied to interpersonal arousal coupling in caregiver-infant dyads.eLife · 2022Article
- Role of the locus coeruleus and basal forebrain in arousal and attention.Brain research bulletin · 2022Review
- Temporal relations between peripheral and central arousals in good and poor sleepers.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Breath chemical markers of sexual arousal in humans.Scientific reports · 2022Article
- Reciprocal relationships between sleep and smell.Frontiers in neural circuits · 2022Review
- Self-organized criticality as a framework for consciousness: A review study.Frontiers in psychology · 2022Article
- Potassium channels and the development of arousal-relevant action potential trains in primary hindbrain neurons.Brain research · 2021Article
- Global waves synchronize the brain's functional systems with fluctuating arousal.Science advances · 2021Article
- Computational animal welfare: towards cognitive architecture models of animal sentience, emotion and wellbeing.Royal Society open science · 2020Review
- Distinguishing pain from nociception, salience, and arousal: How autonomic nervous system activity can improve neuroimaging tests of specificity.NeuroImage · 2020Review
- Diverse Autonomic Nervous System Stress Response Patterns in Childhood Sensory Modulation.Frontiers in integrative neuroscience · 2020Article
- Automated behavioural analysis reveals the basic behavioural repertoire of the urochordate Ciona intestinalis.Scientific reports · 2019Article
- Sleep Disturbances in Child and Adolescent Mental Health Disorders: A Review of the Variability of Objective Sleep Markers.Medical sciences (Basel, Switzerland) · 2018Review
Corrections and comments
- Erratum issued
Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
Why do animals and humans do anything at all? Arousal is the most powerful and essential function of the brain, a continuous function that accounts for the ability of animals and humans to respond to stimuli in the environment by producing muscular responses. Following decades of psychological, neurophysiological and molecular investigations, generalized CNS arousal can now be analyzed using approaches usually applied to physical systems. The concept of "criticality" is a state that illustrates an advantage for arousal systems poised near a phase transition. This property provides speed and sensitivity and facilitates the transition of the system into different brain states, especially as the brain crosses a phase transition from less aroused to more aroused states. In summary, concepts derived from applied mathematics of physical systems will now find their application in this area of neuroscience, the neurobiology of CNS arousal.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.