ArticleBMC musculoskeletal disorders2016
Management of atypical femoral fracture: a scoping review and comprehensive algorithm.
Article in BMC musculoskeletal disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 57 citations in OpenAlex.
- Minimally Invasive Prophylactic Plating for Bisphosphonate-induced Atypical Femoral Fracture Post Total Hip Replacement.Journal of orthopaedic case reports · 2026Article
- Asian Federation of Osteoporosis Societies 2025 consensus on atypical femoral fractures in patients with osteoporosis.Osteoporosis and sarcopenia · 2025Review
- A Novel Approach to Atypical Periprosthetic Femoral Fractures with Stem Breakage: A Case Report.Journal of orthopaedic case reports · 2025Article
- Inflammaging-Driven Osteoporosis: Is a Galectin-Targeted Approach Needed?International journal of molecular sciences · 2025Review
- Unitized Nail-Plate Construct (NPC) for Atypical Femur Fracture Fixation: A Retrospective Study on Clinical Outcomes.Indian journal of orthopaedics · 2025Article
- Atypical Periprosthetic Femoral Fracture Might be Considered a Distinct Subtype of Atypical Femoral Fracture: A Retrospective Study.Orthopaedic surgery · 2024Article
- Atypical Metatarsal Fractures: Report of Five Clinical Cases.Revista brasileira de ortopedia · 2024Article
- Osteoporosis: Molecular Pathology, Diagnostics, and Therapeutics.International journal of molecular sciences · 2023Review
- Surgical strategy of the treatment of atypical femoral fractures.World journal of orthopedics · 2023Review
- Bilateral Atypical Femoral Fractures after Bisphosphonate Treatment for Osteoporosis: A Literature Review.Journal of clinical medicine · 2023Review
- The role of the fracture liaison service in the prevention of atypical femoral fractures.Therapeutic advances in musculoskeletal disease · 2023Review
- Recommendations on the post-acute management of the osteoporotic fracture - Patients with "very-high" Re-fracture risk.Journal of orthopaedic translation · 2022Article
- Bilateral Subtrochanteric Complete Atypical Femoral Fracture in a Patient With Rheumatoid Arthritis: A Case Report.Cureus · 2022Article
- Bilateral Atypical Femur Fractures After Denosumab in a Bisphosphonate Naive Patient: A Case Report.Calcified tissue international · 2022Article
- Plate Fixation for Atypical Fractures of the Femoral Diaphysis.Clinics in orthopedic surgery · 2022Article
- Surgical and Pharmacological Management of Periprosthetic Atypical Femoral Fractures: A Narrative Literature Review.Geriatric orthopaedic surgery & rehabilitation · 2022Article
- Plate osteosynthesis for atypical femoral fractures in patients with severely bowed femurs: comparing short versus long segment fixation - a case series.International journal of burns and trauma · 2022Review
- Health-related quality of life outcomes after surgical treatment of atypical femur fractures: a multicenter retrospective cohort study.JBMR plus · 2021Article
- The Effect of Teriparatide on the Hip: A Literature Review.Hip & pelvis · 2021Review
- Stress Fracture of the Femoral Shaft in Paget's Disease of Bone: A Case Report.Journal of bone metabolism · 2021Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtypical femoral fractures (AFF) are a rare type of femoral stress fracture recently described, potentially associated with prolonged bisphosphonate therapy. Evidence-based recommendations regarding diagnosis and management of these fractures are scarce. The purpose of this study is to propose an algorithm for the diagnosis and management of AFF.
methodsWe performed a PubMed search of the last ten years using the keywords "atypical femoral fractures" and identified further articles through an evaluation of the publications cited in these articles. Relevant studies were included by agreement between researchers, depending on their specialization. Pertinent points of debate were discussed based on the available literature, allowing for consensus regarding the proposed management algorithm.
resultsUsing a systematic approach we performed a scoping review that included a total of 137 articles.
conclusionsA practical guide for diagnosis and management of AFF based on the current concepts is proposed. In spite of the impressive large volume of published literature available since AFF were initially identified, the level of evidence is mostly poor, in particular regarding treatment choice. Therefore, further studies are required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.