Evidence map›Paper›PMID 27215816›Full record

ReviewAnnual review of physical chemistry2016

Molecular Shape and the Hydrophobic Effect.

Matthew B Hillyer, Bruce C Gibb

Abstract readReview
In one paragraph

Review in Annual review of physical chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Water Structure within Ternary Solvents Suggests Nanophase Formation.Journal of the American Chemical Society · 2026
    Article
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  10. Assessing Weak Anion Binding to Small Peptides.The journal of physical chemistry. B · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Learning the relationship between nanoscale chemical patterning and hydrophobicity.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Contribution of hydrophobic interactions to protein mechanical stability.Computational and structural biotechnology journal · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Matthew B HillyerDepartment of Chemistry, Tulane University, New Orleans, Louisiana 70118; email: bgibb@tulane.edu.
Bruce C GibbDepartment of Chemistry, Tulane University, New Orleans, Louisiana 70118; email: bgibb@tulane.edu.

Funding

Using deep-cavity cavitands to study supramolecular chemistry in waterR01GM098141 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI GIBB, BRUCE C · 2012 to 2015
$1.1M
NIGMS NIH HHS R01 GM098141
6 · The paper itself

Abstract

This review focuses on papers published since 2000 on the topic of the properties of solutes in water. More specifically, it evaluates the state of the art of our understanding of the complex relationship between the shape of a hydrophobe and the hydrophobic effect. To highlight this, we present a selection of references covering both empirical and molecular dynamics studies of small (molecular-scale) solutes. These include empirical studies of small molecules, synthetic hosts, crystalline monolayers, and proteins, as well as in silico investigations of entities such as idealized hard and soft spheres, small solutes, hydrophobic plates, artificial concavity, molecular hosts, carbon nanotubes and spheres, and proteins.

Indexed as

AnimalsHumansHydrophobic and Hydrophilic InteractionsMolecular Dynamics SimulationNanotubes, CarbonProteinsThermodynamicsWaterNanotubes, CarbonProteinsWaterhydrationhydrophobic effectnoncovalent interactionssupramolecular chemistrywater

Identifiers

PMID27215816
PMCPMC5571648

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.