ArticleGenome biology2016
What do cells actually want?
Article in Genome biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Relationship between fitness and heterogeneity in exponentially growing microbial populations.Biophysical journal · 2022Article
- Common principles and best practices for engineering microbiomes.Nature reviews. Microbiology · 2019Review
- BOFdat: Generating biomass objective functions for genome-scale metabolic models from experimental data.PLoS computational biology · 2019Article
- Maximum entropy and population heterogeneity in continuous cell cultures.PLoS computational biology · 2019Article
- Human Systems Biology and Metabolic Modelling: A Review-From Disease Metabolism to Precision Medicine.BioMed research international · 2019Review
- A genome-scale metabolic network alignment method within a hypergraph-based framework using a rotational tensor-vector product.Scientific reports · 2018Article
- Modeling the multi-scale mechanisms of macromolecular resource allocation.Current opinion in microbiology · 2018Review
- Characterizing steady states of genome-scale metabolic networks in continuous cell cultures.PLoS computational biology · 2017Article
- Systems Biology Approach to Bioremediation of Nitroaromatics: Constraint-Based Analysis of 2,4,6-Trinitrotoluene Biotransformation by Escherichia coli.Molecules (Basel, Switzerland) · 2017Article
- Genome-scale modeling of yeast: chronology, applications and critical perspectives.FEMS yeast research · 2017Review
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
Abstract
Genome-scale models require an objective function representing what an organism strives for. A method has been developed to infer this fundamental biological function from data.Please see related Research article: www.dx.doi.org/10.1186/s13059-016-0968-2.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.