Evidence map›Paper›PMID 27215602›Full record

ArticleBMC research notes2016

Isolation and detection of microRNA from the egg of chickens.

Ben Wade, Michelle Cummins, Anthony Keyburn, Tamsyn M Crowley

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. The Conundrum of XenomiRs and Human Health.Advances in nutrition (Bethesda, Md.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Ben WadeSchool of Medicine, MMR, Bioinformatics Core Research Facility, Deakin University, Pigdons Road, Waurn Ponds, VIC, 3216, Australia.
Michelle CumminsSchool of Medicine, MMR, Bioinformatics Core Research Facility, Deakin University, Pigdons Road, Waurn Ponds, VIC, 3216, Australia.
Anthony KeyburnCSIRO, Australian Animal Health Laboratory, 5 Portarlington Road, Geelong, VIC, 3220, Australia.
Tamsyn M CrowleySchool of Medicine, MMR, Bioinformatics Core Research Facility, Deakin University, Pigdons Road, Waurn Ponds, VIC, 3216, Australia. tamsyn.crowley@deakin.edu.au.
Commonwealth Scientific and Industrial Research Organisation · AUDeakin University · AUUniversity of New England · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe egg is a vital part of the chicken developmental process and an important protein source for humans. Despite the chicken egg being a subject of intense research little attention has been given to the role of microRNAs within the egg.

findingsWe report a method for the reproducible and reliable isolation of miRNA from the albumen and yolk of chicken eggs. We also report the detection via real-time PCR of a number of miRNAs from both of these biological fluids.

conclusionsThese findings provide an interesting look into the chicken egg and raise questions as to the role that miRNAs maybe playing in the chicken egg. This method of detecting miRNAs in chicken eggs will allow researchers to investigate the presence of an additional level of epigenetic programming in chick development previously unknown and also how this impacts the nutritional value of eggs for human consumption.

Indexed as

EggsAnimalsChickensMicroRNAsReal-Time Polymerase Chain ReactionMicroRNAsAlbumenChickenEggExtractionmicroRNAYolk

Identifiers

PMID27215602
PMCPMC4877990
OpenAlexW2394745923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.