Evidence map›Paper›PMID 27214679›Full record

ReviewAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2016

Micro and Nano Material Carriers for Immunomodulation.

E Bracho-Sanchez, C Q Xia, M J Clare-Salzler, B G Keselowsky

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Review
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  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
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  14. Review
  15. Quantum dot therapeutics: a new class of radical therapies.Journal of biological engineering · 2019
    Review
  16. Solid organ transplantation in the 21Annals of translational medicine · 2018
    Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

E Bracho-SanchezJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL.
C Q XiaDepartment of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL.
M J Clare-SalzlerDepartment of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL.
B G KeselowskyJ. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL.

Funding

Dendritic Cell-Targeting Microparticles for Subcellularly-Targeted Delivery of InR01DK091658 · NIDDK · UNIVERSITY OF FLORIDA · PI KESELOWSKY, BENJAMIN GEORGE · 2012 to 2016
$1.6M
Biomaterial Delivery System for Type 1 Diabetes VaccineR01DK098589 · NIDDK · UNIVERSITY OF FLORIDA · PI KESELOWSKY, BENJAMIN GEORGE · 2014 to 2017
$1.5M
NIDDK NIH HHS R01 DK091658NIDDK NIH HHS R01 DK098589
6 · The paper itself

Abstract

Modulation of the immune system through the use of micro and nano carriers offers opportunities in transplant tolerance, autoimmunity, infectious disease, and cancer. In particular, polymeric, lipid, and inorganic materials have been used as carriers of proteins, nucleic acids, and small drug molecules to direct the immune system toward either suppressive or stimulatory states. Current technologies have focused on the use of particulates or scaffolds, the modulation of materials properties, and the delivery of biologics or small drug molecules to achieve a desired response. Discussed are relevant immunology concepts, the types of biomaterial carriers used for immunomodulation highlighting their benefits and drawbacks, the material properties influencing immune responses, and recent examples in the field of transplant tolerance.

Indexed as

AnimalsBiocompatible MaterialsDrug CarriersHumansImmunomodulationVaccinesBiocompatible MaterialsDrug CarriersVaccinesbasic (laboratory) research/sciencebioengineeringimmune regulationimmunobiologyimmunosuppression/immune modulationvaccine

Identifiers

PMID27214679
PMCPMC5121079

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.