Evidence map›Paper›PMID 27214081›Full record

ArticleBone marrow transplantation2016

The experience of survival following allogeneic haematopoietic stem cell transplantation in New South Wales, Australia.

G Gifford, N Gilroy, G Dyer, L Brice, M Kabir, M Greenwood, S Larsen, J Moore, D Gottlieb, M Hertzberg and 7 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Vitamin requirements during stem cell transplantation: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Pooled it
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  10. Review
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  14. Influenza vaccination in caregivers of childhood cancer survivors.Journal of cancer survivorship : research and practice · 2019
    Article
  15. National Institutes of Health Hematopoietic Cell Transplantation Late Effects Initiative: The Subsequent Neoplasms Working Group Report.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2017
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 8 institutions in 1 country.

G GiffordNorthern Blood Research Centre, Kolling Institute, University of Sydney, Sydney, NSW, Australia.
N GilroyBlood and Marrow Transplant Network, New South Wales Agency for Clinical Innovation, Sydney, NSW, Australia.
G DyerNorthern Clinical School, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia.
L BriceDepartment of Haematology, Royal North Shore Hospital, Sydney, NSW, Australia.
M KabirWestmead Breast Cancer Institute, Sydney, NSW, Australia.
M GreenwoodNorthern Blood Research Centre, Kolling Institute, University of Sydney, Sydney, NSW, Australia.
S LarsenInstitute of Haematology, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
J MooreDepartment of Haematology, St Vincents Hospital, Sydney, NSW, Australia.
D GottliebDepartment of Haematoloy, Westmead Hospital, Sydney, NSW, Australia.
M HertzbergDepartment of Haematology, Prince of Wales Hospital, Sydney, NSW, Australia.
J KwanDepartment of Haematoloy, Westmead Hospital, Sydney, NSW, Australia.
G HuangDepartment of Haematoloy, Westmead Hospital, Sydney, NSW, Australia.
J TanDepartment of Haematology, St Vincents Hospital, Sydney, NSW, Australia.
L BrownDepartment of Haematology, Calvary Mater Hospital, Newcastle, NSW, Australia.
M HoggDepartment of Haematoloy, Westmead Hospital, Sydney, NSW, Australia.
C WardNorthern Blood Research Centre, Kolling Institute, University of Sydney, Sydney, NSW, Australia.
I KerridgeNorthern Blood Research Centre, Kolling Institute, University of Sydney, Sydney, NSW, Australia.
The University of Sydney · AUWestmead Hospital · AUSt Vincent's Hospital Sydney · AUCalvary Mater Newcastle Hospital · AUCancer Institute of New South Wales · AUPrince of Wales Hospital · AURoyal North Shore Hospital · AURoyal Prince Alfred Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allogeneic haematopoietic stem cell transplantation (allo-HSCT) entails long-term morbidities that impair survivors' quality of life through broad physical and psychosocial sequelae. Current data and survival measurements may be inadequate for contemporary Australian allo-HSCT recipients. This study sought to comprehensively describe survivorship in an up-to-date, local setting through validated measurements and a novel questionnaire designed to complement and address limitations of current instruments. All adults who received an allo-HSCT between 2000 and 2012 in New South Wales were eligible and included, if alive, those literate and consenting to the study, which encompassed seven survey instruments. Four hundred and forty-three survivors participated, which is 76% of contactable (n=583) and 66% of eligible survivors (n= 669). Chronic GVHD (cGVHD) and co-morbidity rates were similar to published data. Noteworthy results include prevalent sexual dysfunction (66% females, 52% males), loss of income (low income increased from 21 to 36%, P<0.001) and employment (full-time employment fell from 64 to 33%, P<0.001), suboptimal vaccination (31% complete), and health screening (≈50%). Risk factors for poor vaccination and health screening were cGVHD, younger age, less education, rural/regional residence and transplantation <2 years. This study suggests that improvement in survivorship may necessitate structural changes in the current delivery of health services.

Indexed as

Quality of LifeAdultAgedDelivery of Health CareFemaleGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansMaleMiddle AgedNew South WalesSurveys and QuestionnairesSurvivorsTransplantation, HomologousYoung Adult

Identifiers

PMID27214081
OpenAlexW2398566527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.