Evidence map›Paper›PMID 27214055›Full record

Trial reportJournal of alternative and complementary medicine (New York, N.Y.)2016

Guided Imagery for Total Knee Replacement: A Randomized, Placebo-Controlled Pilot Study.

Ann F Jacobson, Wendy A Umberger, Patrick A Palmieri, Thomas S Alexander, Rodney P Myerscough, Claire B Draucker, Susann Steudte-Schmiedgen, Clemens Kirschbaum

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of alternative and complementary medicine (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06483191 (Acceptability and Feasibility of Acceptance and Commitment Therapy in Total Knee Arthroplasty Patients), which is not on this map. Cited by 14 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 5 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06483191 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Acceptability and Feasibility of Acceptance and Commitment Therapy in Total Knee Arthroplasty Patients

TypeinterventionalSponsorBelfast Health and Social Care TrustRan2025 to 2026Enrolled50ConditionsTotal Knee Arthroplasty, Knee OsteoarthritisArmsAcceptance and Commitment Therapy
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 5 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ann F Jacobson1 Kent State University College of Nursing , Kent, OH.
Wendy A Umberger1 Kent State University College of Nursing , Kent, OH.
Patrick A Palmieri2 Center for the Treatment and Study of Traumatic Stress , Summa Health System, Akron, OH.
Thomas S Alexander3 Department of Immunology, Summa Health System , Akron, OH.
Rodney P Myerscough4 Department of Psychiatry, Summa Health System , Akron, OH.
Claire B Draucker5 Indiana University School of Nursing , Indianapolis, IN.
Susann Steudte-Schmiedgen6 Technische Universität Dresden , Dresden, Germany .
Clemens Kirschbaum6 Technische Universität Dresden , Dresden, Germany .
Summa Health System · USKent State University · USTU Dresden · DEIndiana University – Purdue University Indianapolis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the effect of guided imagery (GI) on functional outcomes of total knee replacement (TKR), explore psychological and neuroimmune mediators, and assess feasibility of study implementation.

designInvestigator-blinded, randomized, placebo-controlled pilot study. SETTINGS: Hospital, surgeon's office, participant's home.

participants82 persons undergoing TKR.

interventionsAudiorecordings of TKR-specific GI scripts or placebo-control audiorecordings of audiobook segments. OUTCOME MEASURES: Gait velocity and Western Ontario and McMaster Universities Arthritis Index (WOMAC) Function scale.

resultsOutcomes for 58 participants (29 receiving GI and 29 controls) were analyzed at 6 months after surgery. The most frequent reason for noncompletion was protocol-driven exclusion at 6 months for having the contralateral knee replaced before the study endpoint (n = 15). With imaging ability as a moderator, gait velocity, but not WOMAC Function score, was significantly improved at 6 months in the GI group. Participants in the GI group, but not the control group, had lower WOMAC Pain scores at 3 weeks after surgery than at baseline. Hair cortisol concentration was significantly lower at 6 months after surgery than at baseline in the GI group but not the control group. GI group participants had lower treatment adherence but greater treatment credibility than the control group.

conclusionRandomized controlled trials of GI in the TKR population are feasible, but inclusion/exclusion criteria influence attrition. Further studies are needed to elaborate this study's findings, which suggest that guided imagery improves objective, but not patient-reported, outcomes of TKR. Hair cortisol concentration results suggest that engagement in a time-limited guided imagery intervention may contribute to stress reduction even after the intervention is terminated. Further investigation into optimal content and dosing of GI is needed.

Indexed as

AgedAged, 80 and overArthroplasty, Replacement, KneeFeasibility StudiesFemaleHumansImagery, PsychotherapyMaleMiddle AgedPilot Projects

Identifiers

PMID27214055
PMCPMC4939380
OpenAlexW2403298082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.