Evidence map›Paper›PMID 27213371›Full record

ReviewInternational journal of molecular sciences2016

Functions of miRNAs during Mammalian Heart Development.

Shun Yan, Kai Jiao

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
  2. Cells · 2025
    Article
  3. Article
  4. Article
  5. Cardiac microRNAs: diagnostic and therapeutic potential.Archives of medical science : AMS · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Hotspot Mutations in DICER1 Causing GLOW Syndrome-Associated MacrocephalyMicroRNA (Shariqah, United Arab Emirates) · 2020
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shun YanDepartment of Genetics, the University of Alabama at Birmingham, Birmingham, AL 35294, USA. syan@uab.edu.
Kai JiaoDepartment of Genetics, the University of Alabama at Birmingham, Birmingham, AL 35294, USA. kjiao@uab.edu.

Funding

The Roles of Semaphorin Signaling During Valvuloseptal DevelopmentR01HL095783 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JIAO, KAI · 2010 to 2021
$3.4M
Molecular mechanisms regulating mouse valvulogenesisR03HD082634 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JIAO, KAI · 2014 to 2015
$145k
NHLBI NIH HHS R01 HL095783NICHD NIH HHS R03 HD082634
6 · The paper itself

Abstract

MicroRNAs (miRNAs) play essential roles during mammalian heart development and have emerged as attractive therapeutic targets for cardiovascular diseases. The mammalian embryonic heart is mainly derived from four major cell types during development. These include cardiomyocytes, endocardial cells, epicardial cells, and neural crest cells. Recent data have identified various miRNAs as critical regulators of the proper differentiation, proliferation, and survival of these cell types. In this review, we briefly introduce the contemporary understanding of mammalian cardiac development. We also focus on recent developments in the field of cardiac miRNAs and their functions during the development of different cell types.

Indexed as

AnimalsCardiovascular DiseasesCell DifferentiationCell ProliferationEndocardiumGene Expression Regulation, DevelopmentalHeartHumansMammalsMicroRNAsMyocytes, CardiacNeural CrestPericardiumMicroRNAscardiogenesisDicer1miRNA

Identifiers

PMID27213371
PMCPMC4881605

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.