Evidence map›Paper›PMID 27213167›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2016

Processing to determine optical parameters of atherosclerotic disease from phantom and clinical intravascular optical coherence tomography three-dimensional pullbacks.

Ronny Shalev, Madhusudhana Gargesha, David Prabhu, Kentaro Tanaka, Andrew M Rollins, Guy Lamouche, Charles-Etienne Bisaillon, Hiram G Bezerra, Soumya Ray, David L Wilson

Abstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ronny ShalevCase Western Reserve University , Department of Electrical Engineering and Computer Science, Cleveland, Ohio 44106, United States.
Madhusudhana GargeshaCase Western Reserve University , Department of Biomedical Engineering, Cleveland, Ohio 44106, United States.
David PrabhuCase Western Reserve University , Department of Biomedical Engineering, Cleveland, Ohio 44106, United States.
Kentaro TanakaUniversity Hospitals Case Medical Center , Harrington Heart and Vascular Institute, Imaging Core Laboratory, Cleveland, Ohio 44106, United States.
Andrew M RollinsCase Western Reserve University , Department of Biomedical Engineering, Cleveland, Ohio 44106, United States.
Guy LamoucheNational Research Council , 75, de Mortagne, Boucherville, Quebec J4B 6Y4, Canada.
Charles-Etienne BisaillonNational Research Council , 75, de Mortagne, Boucherville, Quebec J4B 6Y4, Canada.
Hiram G BezerraUniversity Hospitals Case Medical Center , Harrington Heart and Vascular Institute, Imaging Core Laboratory, Cleveland, Ohio 44106, United States.
Soumya RayCase Western Reserve University , Department of Electrical Engineering and Computer Science, Cleveland, Ohio 44106, United States.
David L WilsonCase Western Reserve University, Department of Biomedical Engineering, Cleveland, Ohio 44106, United States; Case Western Reserve University, Department of Radiology, Cleveland, Ohio 44106, United States.

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024989 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI DAVIS, PAMELA B · 2007 to 2011
$53.7M
In vivo Characterization of Stents using Intravascular OCT ImagingR01HL114406 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI BEZERRA, HIRAM, ROLLINS, ANDREW MARTIN · 2013 to 2016
$1.7M
Coronary Plaque Characterization with Vascular OCT ImagingR21HL108263 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI COSTA, MARCO A, WILSON, DAVID LYNN · 2011 to 2012
$423k
NCRR NIH HHS UL1 RR024989NHLBI NIH HHS R01 HL114406NHLBI NIH HHS R21 HL108263
6 · The paper itself

Abstract

Analysis of intravascular optical coherence tomography (IVOCT) data has potential for real-time in vivo plaque classification. We developed a processing pipeline on a three-dimensional local region of support for estimation of optical properties of atherosclerotic plaques from coronary artery, IVOCT pullbacks. Using realistic coronary artery disease phantoms, we determined insignificant differences in mean and standard deviation estimates between our pullback analyses and more conventional processing of stationary acquisitions with frame averaging. There was no effect of tissue depth or oblique imaging on pullback parameter estimates. The method's performance was assessed in comparison with observer-defined standards using clinical pullback data. Values (calcium [Formula: see text], lipid [Formula: see text], and fibrous [Formula: see text]) were consistent with previous measurements obtained by other means. Using optical parameters ([Formula: see text], [Formula: see text], [Formula: see text]), we achieved feature space separation of plaque types and classification accuracy of [Formula: see text]. Despite the rapid [Formula: see text] motion and varying incidence angle in pullbacks, the proposed computational pipeline appears to work as well as a more standard "stationary" approach.

Indexed as

optical coherence tomographyparameters

Identifiers

PMID27213167
PMCPMC4865531

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.