Evidence map›Paper›PMID 27213080›Full record

ArticleParkinson's disease2016

Reliability of Three Disability Scales for Detection of Independence Loss in Parkinson's Disease.

Anders Bjornestad, Ole-Bjorn Tysnes, Jan Petter Larsen, Guido Alves

Abstract read
In one paragraph

Article in Parkinson's disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  6. Article
  7. Article
  8. Detecting Effect of Levodopa in Parkinson's Disease Patients Using Sustained Phonemes.IEEE journal of translational engineering in health and medicine · 2021
    Article
  9. Review
  10. Article
  11. The impact of freezing of gait on functional dependency in Parkinson's disease with regard to motor phenotype.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anders BjornestadThe Norwegian Centre for Movement Disorders, Stavanger University Hospital, 4068 Stavanger, Norway; Institute of Clinical Medicine, University of Bergen, 5021 Bergen, Norway; Department of Neurology, Stavanger University Hospital, 4068 Stavanger, Norway.
Ole-Bjorn TysnesInstitute of Clinical Medicine, University of Bergen, 5021 Bergen, Norway; Department of Neurology, Haukeland University Hospital, 5021 Bergen, Norway.
Jan Petter LarsenThe Norwegian Centre for Movement Disorders, Stavanger University Hospital, 4068 Stavanger, Norway.
Guido AlvesThe Norwegian Centre for Movement Disorders, Stavanger University Hospital, 4068 Stavanger, Norway; Department of Neurology, Stavanger University Hospital, 4068 Stavanger, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background. Loss of independence is considered an important outcome measure in Parkinson's disease (PD), but tools to assess dependency have not been tested in PD. Methods. In this study of 158 PD patients, we examined the two most widely used scales and cut-offs for dependency evaluation in PD, the Hoehn and Yahr (HY) stage > 3 and the Schwab and England (SE) scale score < 80%, against a standardized clinical interview assessing dependency in activities of daily living (ADL). We also examined the performance of the generic Barthel ADL index. In addition, we determined whether alternative cut-offs improved the utility of these tools. Results. Compared to clinical interview as gold standard, HY stage > 3 had 21% sensitivity and 98% specificity in detecting dependency in ADL. Corresponding figures for SE score < 80% were 55% and 92%, respectively. Using alternative cut-off values improved the overall diagnostic accuracy only slightly. Barthel ADL index had 67% sensitivity and 78% specificity in detecting dependency at its optimal cut-off value. Conclusion. Both the disease-specific HY staging and SE scale and the generic Barthel ADL index are suboptimal tools for assessing independence loss in PD. Clinical interview should be the assessment of choice in studies of dependency.

Identifiers

PMID27213080
PMCPMC4860247

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.