ArticleBMC hematology2016
Prevalence of neutropenia in children by nationality.
Article in BMC hematology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 40 citations in OpenAlex.
- Community-acquiredFrontiers in pediatrics · 2025Article
- Prevalence of neutropenia in US residents: a population based analysis of NHANES 2011-2018.BMC public health · 2023Article
- Article
- Autoimmune Neutropenias: Update on Clinical and Biological Features in Children and Adults.HemaSphere · 2023Review
- Hematological indices reference intervals for a healthy Arab population in Qatar: Effect of age, gender, and geographic location.Medicine · 2022Article
- GMMA Technology for the Development of Safe Vaccines: Meta-Analysis of Individual Patient Data to Assess the Safety Profile of Shigella sonnei 1790GAHB Vaccine in Healthy Adults, with Special Focus on Neutropenia.Infectious diseases and therapy · 2022Article
- Hematological indices in pediatric patients with acyanotic congenital heart disease: a cross-sectional study of 248 patients.The Egyptian journal of medical human genetics · 2022Article
- Isolated Neutropenia/Benign Ethnic Neutropenia: A Common Clinical and Laboratory Finding in Southern and Western Saudi Arabia.International journal of general medicine · 2021Article
- The Prevalence of Isolated Neutropenia at High Altitude in Southern Saudi Arabia: Does Altitude Affect Leucocyte Count?International journal of general medicine · 2020Article
- Neutropenia in Pediatric Infections.Indian journal of pediatrics · 2019Article
- Clinical Profile and Short Term Outcome of Children with Neutropenia.Indian journal of pediatrics · 2019Article
- Neutrophil Counts in Healthy South African Infants: Implications for Enrollment and Adverse Event Grading in Clinical Trials in an African Setting.The journal of pediatrics: X · 2019Article
- Severe congenital neutropenias.Nature reviews. Disease primers · 2017Review
- An update on the diagnosis and treatment of chronic idiopathic neutropenia.Current opinion in hematology · 2017Review
- Chronic neutropenia in childhood: experience of a tertiary center.Jornal de pediatriaObservational
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA high prevalence of neutropenia has been reported in several ethnic groups amongst whom many healthy individuals with low neutrophil counts undergo unnecessary investigations. This study aims to ascertain the prevalence of neutropenia (NP) in a large cohort of children from North African, Middle Eastern, and Asian countries residing in the United Arab Emirates.
methodsNeutrophil counts of 26,542 children (one day to six years of age) from 86 countries were analyzed. The subjects were enrolled in the Well-Child-Care program of Ambulatory Health Services of Emirate of Abu Dhabi, United Arab Emirates. NP was defined as a neutrophil count <1.5 × 10(9)/L and severe NP <0.5 × 10(9)/L.
resultsThe neutrophil counts reached a nadir in the fourth week of life and changed slightly from the age of six-months to six-years. The frequency of NP was (from West-to-East): North African Arabs 15.4 %, Green Crescent Arabs 9.8 %, Peninsular Arabs 10.9 %, Iranians 3.1 %, Afghanis 2.5 %, Pakistanis 5.6 %, Indians 10.2 %, and Filipinos 7.3 %. The frequency of severe NP in North African Arabs (Sudanese) was 2.8 %, Green Crescent and Peninsular Arabs ≤1 %, Indians 1.5 %, and Filipinos 1.8 %. In 12,703 Emirati children, the frequency of NP was 10.6 % similar to their adult counterparts.
conclusionThe prevalence of childhood NP varied considerably by geoethnicity. Measures to prevent the inappropriate investigations of healthy children with benign neutropenia are proposed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.