Evidence map›Paper›PMID 27213035›Full record

ArticleChemical science2016

Nickel-Catalyzed Arylation of Heteroaryl-containing Diarylmethanes: Exceptional Reactivity of the Ni(NIXANTPHOS)-based Catalyst.

Xinyu Cao, Sheng-Chun Sha, Minyan Li, Byeong-Seon Kim, Catherine Morgan, Rudan Huang, Xiaodong Yang, Patrick J Walsh

Abstract read
In one paragraph

Article in Chemical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Regio- and chemoselective CspChemical science · 2018
    Article
  9. Article
  10. Article
  11. Transition-Metal-Free Radical C(spJournal of the American Chemical Society · 2017
    Article
  12. Article
  13. Article
  14. Article
  15. Tandem C(spAdvanced synthesis & catalysis · 2016
    Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinyu CaoKey Laboratory of Cluster Science of Ministry of Education, School of Chemistry, Beijing Institute of Technology, Beijing 100081, PR China; Department of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.
Sheng-Chun ShaDepartment of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.
Minyan LiDepartment of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.
Byeong-Seon KimDepartment of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.
Catherine MorganDepartment of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.
Rudan HuangKey Laboratory of Cluster Science of Ministry of Education, School of Chemistry, Beijing Institute of Technology, Beijing 100081, PR China.
Xiaodong YangKey Laboratory of Medicinal Chemistry for Natural Resource, School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China.
Patrick J WalshDepartment of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.

Funding

Arylation of weakly acidic sp3 hybridized C-H'sR01GM104349 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI WALSH, PATRICK J · 2013 to 2016
$1.3M
NIGMS NIH HHS R01 GM104349
6 · The paper itself

Abstract

Nickel(0)-catalyzed cross-coupling of heteroaryl-containing diarylmethanes with both aryl bromides and chlorides has been achieved. The success of this reaction relies on the introduction of a unique nickel/NIXANTPHOS-based catalyst system, which provides a direct route to triarylmethanes from heteroaryl-containing diarylmethanes. Reactivity studies indicate the Ni(NIXANTPHOS)-based catalyst exhibits enhanced reactivity over XANTPHOS derivatives and other Ni(phosphine)-based catalysts in the reactions examined.

Identifiers

PMID27213035
PMCPMC4869726

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.