Evidence map›Paper›PMID 27213034›Full record

ArticleChemical science2015

Heterometallic titanium-gold complexes inhibit renal cancer cells

Jacob Fernández-Gallardo, Benelita T Elie, Tanmoy Sadhukha, Swayam Prabha, Mercedes Sanaú, Susan A Rotenberg, Joe W Ramos, María Contel

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 119 citations in OpenAlex.

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  19. SEC hyphenated to a multielement-specific detector unravels the degradation pathway of a bimetallic anticancer complex in human plasma.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Jacob Fernández-Gallardo *Department of Chemistry, Brooklyn College and The Graduate Center, The City University of New York, Brooklyn, NY, 11210, US.
Benelita T Elie *Department of Chemistry, Brooklyn College and The Graduate Center, The City University of New York, Brooklyn, NY, 11210, US.
Tanmoy SadhukhaDepartment of Pharmaceutics, College of Pharmacy, University of Minnesota, MN, 55455, US.
Swayam PrabhaDepartment of Pharmaceutics, College of Pharmacy, University of Minnesota, MN, 55455, US.
Mercedes SanaúDepartamento de Química Inorgánica, Universidad de Valencia, Burjassot, Valencia, 46100, Spain.
Susan A RotenbergBiology PhD Program, The Graduate Center, The City University of New York, 365 Fifth Avenue, New York, NY, 10016, US.
Joe W RamosCancer Biology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa, Honolulu, HI, 96813, US.
María ContelDepartment of Chemistry, Brooklyn College and The Graduate Center, The City University of New York, Brooklyn, NY, 11210, US.
The Graduate Center, CUNY · USUniversity of Hawaiʻi at Mānoa · USUniversity of Minnesota · USQueens College, CUNY · USUniversitat de València · ES

Funding

University of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Xin Chen · 1996 to 2026
$56.2M
Titanium-gold-based chemotherapeutics for prostate and kidney cancerSC1CA182844 · NCI · BROOKLYN COLLEGE · PI CONTEL, MARIA · 2013 to 2016
$1.4M
RSK-2 regulates integrin-mediated adhesion and migrationR01GM088266 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI RAMOS, JOE WILLIAM · 2010 to 2013
$1.4M
NCI NIH HHS P30 CA071789NCI NIH HHS SC1 CA182844NIGMS NIH HHS R01 GM088266
6 · The paper itself

Abstract

Following recent work on heterometallic titanocene-gold complexes as potential chemotherapeutics for renal cancer, we report here on the synthesis, characterization and stability studies of new titanocene complexes containing a methyl group and a carboxylate ligand (mba = S-C

Identifiers

PMID27213034
PMCPMC4869729
OpenAlexW2099932563

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.