Evidence map›Paper›PMID 27212838›Full record

ArticleBioinformation2016

Classification of anti hepatitis peptides using Support Vector Machine with hybrid Ant Colony OptimizationThe Luxembourg database of trichothecene type B F. graminearum and F. culmorum producers.

Gunjan Mishra, Vivek Ananth, Kalpesh Shelke, Deepak Sehgal, Jayaraman Deepak

Abstract read
In one paragraph

Article in Bioinformation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gunjan MishraShiv Nadar University, Gautam Budha Nagar, U.P 201314.
Vivek AnanthShiv Nadar University, Gautam Budha Nagar, U.P 201314.
Kalpesh ShelkeCentre for Modeling and Simulation, Pune University, Pune 4110001.
Deepak SehgalShiv Nadar University, Gautam Budha Nagar, U.P 201314.
Jayaraman DeepakShiv Nadar University, Gautam Budha Nagar, U.P 201314.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis is an emerging global threat to public health due to associated mortality, morbidity, cancer and HIV co-infection. Available diagnostics and therapeutics are inadequate to intercept the course and transmission of the disease. Antimicrobial peptides (AMP) are widely studied and broad-spectrum host defense peptides are investigated as a targeted anti-viral. Therefore, it is of interest to describe the supervised identification of anti-hepatitis peptides. We used a hybrid Support Vector Machine (SVM) with Ant Colony Optimization (ACO) algorithm for simultaneous classification and domain feature selection. The described model shows a 10 fold cross-validation accuracy of 94 percent. This is a reliable and a useful tool for the prediction and identification of hepatitis specific drug activity.

Identifiers

PMID27212838
PMCPMC4857459

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.