Evidence map›Paper›PMID 27212807›Full record

ReviewMediators of inflammation2016

Immune Cells in Cancer Therapy and Drug Delivery.

Ceren Eyileten, Kinga Majchrzak, Zofia Pilch, Katarzyna Tonecka, Joanna Mucha, Bartlomiej Taciak, Katarzyna Ulewicz, Katarzyna Witt, Alberto Boffi, Magdalena Krol and 1 more

Abstract readReview
In one paragraph

Review in Mediators of inflammation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Frontiers in immunology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ceren EyiletenDepartment of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 166, 02-787 Warsaw, Poland.
Kinga MajchrzakDepartment of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 166, 02-787 Warsaw, Poland.
Zofia PilchDepartment of Immunology, Center for Biostructure Research, Medical University of Warsaw, Banacha 1a, 02-089 Warsaw, Poland; Cellis Sp. z o.o., Gen. Zajaczka 28, 01-510 Warsaw, Poland.
Katarzyna ToneckaDepartment of Immunology, Center for Biostructure Research, Medical University of Warsaw, Banacha 1a, 02-089 Warsaw, Poland; Cellis Sp. z o.o., Gen. Zajaczka 28, 01-510 Warsaw, Poland.
Joanna MuchaDepartment of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 166, 02-787 Warsaw, Poland.
Bartlomiej TaciakDepartment of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 166, 02-787 Warsaw, Poland; Cellis Sp. z o.o., Gen. Zajaczka 28, 01-510 Warsaw, Poland.
Katarzyna UlewiczDepartment of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 166, 02-787 Warsaw, Poland; Cellis Sp. z o.o., Gen. Zajaczka 28, 01-510 Warsaw, Poland.
Katarzyna WittDepartment of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 166, 02-787 Warsaw, Poland.
Alberto BoffiDepartment of Biochemical Sciences, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy.
Magdalena KrolDepartment of Physiological Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 166, 02-787 Warsaw, Poland; Department of Immunology, Center for Biostructure Research, Medical University of Warsaw, Banacha 1a, 02-089 Warsaw, Poland.
Tomasz P RygielDepartment of Immunology, Center for Biostructure Research, Medical University of Warsaw, Banacha 1a, 02-089 Warsaw, Poland; Cellis Sp. z o.o., Gen. Zajaczka 28, 01-510 Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies indicate the critical role of tumour associated macrophages, tumour associated neutrophils, dendritic cells, T lymphocytes, and natural killer cells in tumourigenesis. These cells can have a significant impact on the tumour microenvironment via their production of cytokines and chemokines. Additionally, products secreted from all these cells have defined specific roles in regulating tumour cell proliferation, angiogenesis, and metastasis. They act in a protumour capacity in vivo as evidenced by the recent studies indicating that macrophages, T cells, and neutrophils may be manipulated to exhibit cytotoxic activity against tumours. Therefore therapy targeting these cells may be promising, or they may constitute drug or anticancer particles delivery systems to the tumours. Herein, we discussed all these possibilities that may be used in cancer treatment.

Indexed as

AnimalsHumansMacrophagesNeoplasmsNeutrophilsT-LymphocytesTumor Microenvironment

Identifiers

PMID27212807
PMCPMC4860248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.