Evidence map›Paper›PMID 27212128›Full record

SynthesisAsian journal of andrology

Comparison of surgical effect and postoperative patient experience between laparoendoscopic single-site and conventional laparoscopic varicocelectomy: a systematic review and meta-analysis.

Zheng Zhang, Shu-Juan Zheng, Wen Yu, You-Feng Han, Hai Chen, Yun Chen, Yu-Tian Dai

Abstract readComparative StudyMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zheng ZhangDepartment of Andrology, Affiliated Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing 210008, China.
Shu-Juan ZhengDepartment of Andrology, Affiliated Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing 210008, China.
Wen YuDepartment of Andrology, Affiliated Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing 210008, China.
You-Feng HanDepartment of Andrology, Affiliated Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing 210008, China.
Hai ChenDepartment of Andrology, Affiliated Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing 210008, China.
Yun ChenDepartment of Andrology, Affiliated Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing 210008, China.
Yu-Tian DaiDepartment of Andrology, Affiliated Drum Tower Hospital, School of Medicine, Nanjing University, Nanjing 210008, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present meta-analysis was conducted to compare the clinical effect and patient experience of laparoendoscopic single-site varicocelectomy (LESSV) and conventional laparoscopic varicocelectomy. The candidate studies were included after literature search of database Cochrane Library, PubMed, EMBASE, and MEDLINE. Related information on essential data and outcome measures was extracted from the eligible studies by two independent authors, and a meta-analysis was conducted using STATA 12.0 software. Subgroup analyses were conducted by study design (RCT and non-RCT). The odds ratio (OR) or standardized mean difference (SMD) and their 95% confidence intervals (95% CIs) were used to estimate the outcome measures. Seven articles were included in our meta-analysis. The results indicated that patient who had undergone LESSV had a shorter duration of back to work (overall: SMD = -1.454, 95% CI: -2.502--0.405, P = 0.007; non-RCT: SMD = -2.906, 95% CI: -3.796--2.017, P = 0.000; and RCT: SMD = -0.841, 95% CI: -1.393--0.289, P = 0.003) and less pain experience at 3 h or 6 h (SMD = -0.447, 95% CI: -0.754--0.139, P = 0.004), day 1 (SMD = -0.477, 95% CI: -0.905--0.05, P = 0.029), and day 2 (SMD = -0.612, 95% CI: -1.099--0.125, P = 0.014) postoperatively based on RCT studies. However, the meta-analyses based on operation time, clinical effect (improvement of semen quality and scrotal pain relief), and complications (hydrocele and recurrence) yielded nonsignificant results. In conclusion, LESSV had a rapid recovery and less pain experience over conventional laparoscopic varicocelectomy. However, there was no statistically significant difference between the two varicocelectomy techniques in terms of the clinical effect and the incidence of hydrocele and varicocele recurrence. More high-quality studies are warranted for a comprehensive conclusion.

Indexed as

EndoscopyHumansLaparoscopyMaleOperative TimePatient SatisfactionPostoperative ComplicationsPostoperative PainSemen AnalysisTesticular HydroceleTreatment OutcomeUrologic Surgical Procedures, MaleVaricocele

Identifiers

PMID27212128
PMCPMC5312228

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.